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Proteomics and phosphoproteomics of human colorectal cancer cells lacking a s...

Han(B),Lim(HJ),Kim(SJ),Shin(J),Kim(HH),Kim... Anim Cells Syst (Seoul) None

...PIK3CA, and PAK4, using HCT-116, a human colorectal cancer cell line. Using CRISPR-Cas9, we generated individual knockou...

Detection of Cancer-Associated Mutations Using Primer Exchange Reaction-Based...

Kocabey(S),Rüegg(C) Small Sci 2026-02-00

...PIK3CA E545K/A and P53 R280K mutations, consistent with Sanger sequencing results and validating our method for liquid b...

Case Report: Mixed ductal-lobular carcinoma consisting of invasive lobular ca...

Kawachi(K),Tang(X),Kasajima(R),Katayama(K)... Front Oncol None

...PIK3CA were identified in the gILC region, whereas only two nonsynonymous SNVs in SMAD4 and PIK3CA were identified in th...

Clinical and biological characteristics associated with loss-of-heterozygosit...

Blanc-Durand(F),Rouleau(E),Pautier(P),Ngoi... J Gynecol Oncol 2026-01-00

...PIK3CA, CTNNB1, and PTEN mutations. The median overall survival was 42.2, 55.2, and 100.8 months in the LOH-high, interm...

Genomic and epigenomic diversity of breast cancer across Western and MENA pop...

Shaikh(S),Akbar(A),Khalifey(HT),Raziq(T),A... Front Oncol 2026-00-00

...PIK3CA for roughly 10% of curated somatic mutation records pooled across 44 studies (proportions of mutation calls, not ...

PIK3CA in Cancer: Structure, Biology, Alterations, and Actionability.

Ottaiano(A),Picone(C),Santorsola(M),Berret... Cancers (Basel) 2026-08-28

PIK3CA, which encodes the p110α catalytic subunit of phosphoinositide 3-kinase (PI3K), is one of the most frequently alt...

Intratumoral Human Papillomavirus in Advanced Prostate Cancer: Systematic Rev...

Brenna(D),Puglisi(M),Epistolio(S),Barizzi(... Int J Mol Sci 2026-09-01

...PIK3CA, and AR amplification. IT-HPV seems to be infrequent in metastatic and locally advanced PCa in Western population...

Functional Characterization of Putative Novel MicroRNA-1133 in the Antioxidan...

Othman(NS),Aminuddin(A),Hamid(AA),Abidin(S... Int J Mol Sci 2026-08-24

...PIK3CA as a biologically plausible candidate target for further investigation. This study investigated the functional si...

Tumor genomic landscape of older patients with metastatic breast cancer☆.

Gupta(H),Brantley(KD),Grinda(T),Freedman(R... ESMO Open 2026-09-14

...PIK3CA (44%), TP53 (33%), CDH1 (22%) and amplifications in CCND1 (18%). After adjustment, older age was associated with ...

Integration of FAERS database and network toxicology to investigate adverse d...

Xu(B),Zhou(X),Xie(Y),Zhou(W) Naunyn Schmiedebergs Arch P... 2026-08-27

...PIK3CA, TNF, RELA, BCL2, and AKT1 as core targets. Molecular docking suggested potential binding interactions, with itra...

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