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Germline Genetic Testing in Breast and Gynecologic Cancers: Evaluating Age at...

Papadopoulou(E),Tsaousis(GN),Alevizou(R),A... Cancers (Basel) 2026-05-10

...BRCA1 showed stronger age enrichment than BRCA2 (8.14% vs. 3.16% in <40 y; median diagnosis 43 vs. 45 years). Age remain...

The Current Landscape of Metastatic Breast Cancer: A Pathology Guide on Emerg...

Ferreira(J),Albergaria(A),Schmitt(F) Cancers (Basel) 2026-05-10

...BRCA1/2, and PD-L1 expression. Furthermore, liquid biopsy, particularly the analysis of circulating tumor DNA (ctDNA), i...

Centralized Homologous Recombination Repair Testing in Metastatic Castration-...

Caramelo(B),García-Berbel(P),Carmen(SD),Ca... Cancers (Basel) 2026-05-16

...BRCA1, BRCA2, CHEK2, ATM, and CDK12. Results: HRR gene pathogenic or likely pathogenic alterations were identified in 18...

Genomic Biomarkers for First-Line Treatment Selection in Metastatic Pancreati...

Muddasani(A),Abdelnoor(A),Manne(A) Cancers (Basel) 2026-05-21

...BRCA1/2) or partner and localizer of BRCA2 (PALB2), as well as broader genomic scar signatures. Transcriptomic subtype a...

SYTL4 May Serve as a New Predictive Biomarker for Survival and Trastuzumab Tr...

Kordowitzki(P) Int J Mol Sci 2026-05-18

...BRCA1 mutations, suggesting a mechanistic interplay between BRCA1-driven genomic instability and SYTL4-regulated signali...

Synergistic Co-Delivery of siFGF2 and Doxorubicin via QTPlus Nanoparticles fo...

Xia(X),Zhang(Z),Zhang(J),Feng(K),Wang(Y),L... Pharmaceutics 2026-05-10

...BRCA1 (4.041-fold). Flow cytometry showed markedly increased apoptosis (78.5% vs. 42.65% for QTPlus-DOX alone). In the M...

Deep Learning and Experimental Validation of BRCA1-Associated Protein-1 Misse...

Davé(N),Taylor Gonzalez(DJ),Djulbegovic(MB... Ophthalmol Sci 2026-07-00

...BRCA1-associated protein-1 (BAP1) missense variants in uveal melanoma (UM). Cross-sectional analytical study comparing c...

Durable complete remission of pulmonary metastases with bevacizumab plus olap...

Iida(Y),Saito(Y),Shimazaki(M),Ichikawa(T),... Gynecol Oncol Rep 2026-06-00

...BRCA1/2 mutations. After six cycles of chemotherapy, the pulmonary lesions showed a partial response. Maintenance therap...

Navigating the healthcare system with a BRCA1/2 pathogenic variant: What do p...

Karimaghaie(T),Webster(EM),Levi(SR),Blank(... Gynecol Oncol Rep 2026-06-00

...BRCA1/2 PV-related needs (26, 96%) and same-day appointments (25, 93%). Participants preferred BRCA1/2 PV expertise amon...

Higher Levels of BRCA1 Gene Methylation in Sporadic Breast Cancer Patients wi...

Agnes(G),Damin(APS),Watte(G),Guimarães(GR)... Med Sci (Basel) 2026-05-13

...BRCA1 and BRCA2 genes showed methylation, and there was a higher level of BRCA1 gene methylation in patients without rec...

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