...PIK3CA gene (p.H1047R and p.E545K mutations) by the quantitative polymerase chain reaction technique. Expression of sele...
...PIK3CA, and TP53 genes. Moreover, we observed that a portion of the lung cancer samples harbored two or more mutations i...
...PIK3CA, TP53, AXIN1, PTEN or APC genes leading to the dedifferentiation of the tumors, are described.,DNAs from fresh fr...
...PIK3CA mutation status (n = 53), or PAM50 gene expression subtype (n = 55) did not. Five of the six long-term responders...
...PIK3CA mutations or amplification. Studying models of therapeutic resistance, we have observed that SCC cells that becom...
...PIK3CA mutations were evaluated using peptide nucleic acid-locked nucleic acid polymerase chain reaction clamp reactions...
...PIK3CA and AKT2 mutations occurred at low frequency in GC, and suggest that the PIK3CA/AKT2 pathway might engage other e...
...PIK3CA genes were analyzed for mutations.,A significantly higher expression of ER and PR, and a lower expression of L1CA...
...PIK3CA had a significantly higher response rate than patients with these alterations (p=0.006). In the logistic regressi...
...PIK3CA mutation.,(1) To determine the role of oncogene dependence on PIK3CA-one of the more common and targetable oncoge...
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