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TP53 BRCA1 CRISPR single-cell cancer

Niravath(Polly),Eble(Tanya),Contreras(Alej... Exp Hematol Oncol 2015-02-11

...PIK3CA (c. 1624 G > A, p.E42K) and a heterozygous 13-basepair deletion in TP53 (c.639-651del, p.H214fs). The small cell ...

Kuete(Victor),Saeed(Mohamed E M),Kadioglu(... Phytomedicine 2015-03-31

...PIK3CA protein structures revealed similar binding energies to wortmannin than wild-type PIK3CA. This protein is the pri...

Shinozaki-Ushiku(Aya),Kunita(Akiko),Fukaya... Int J Oncol 2015-12-07

...PIK3CA and ARID1A and amplification of JAK2 and PD-L1/L2. Global CpG island hypermethylation, which induces epigenetic s...

Schechter(Rebecca B),Nagilla(Madhavi),Jose... Cancer Lett 2015-04-20

...PIK3CA (H1047R) mutation. qPCR showed increased copy numbers of PIK3CA in 6 (33%) tumors, VEGFR1 in 0 (0%) tumors, VEGFR...

Mao(Chen),Wu(Xin-Yin),Yang(Zu-Yao),Threapl... Sci Rep 2015-11-20

Current data on the concordance of KRAS, BRAF, PIK3CA mutation status or PTEN expression status between primary tumors a...

Manceau(Gilles),Marisa(Laetitia),Boige(Val... Cancer Med 2015-12-17

...PIK3CA mutation. In the retrospective training cohort (n = 433), patients with PIK3CA-mutated MSS tumors (n = 47) experi...

Keppler-Noreuil(Kim M),Rios(Jonathan J),Pa... Am J Med Genet A 2015-09-16

...PIK3CA activating mutations have included Fibroadipose hyperplasia or Overgrowth (FAO), Hemihyperplasia Multiple Lipomat...

Cheaib(Bianca),Auguste(Aurélie),Leary(Alex... Chin J Cancer 2015-06-04

...PIK3CA) and/or phosphatase and tensin homolog (PTEN) alterations, may be particularly suited to this approach. Given the...

Wen(Feifei),He(Shuang),Sun(Chenbo),Li(Tang... Int J Clin Exp Pathol 2015-09-22

...PIK3CA and PIK3CB expression and the MDR gene in colorectal cancer (CRC) patients. Immunohistochemistry was employed to ...

Chang(Li-Chun),Chiu(Han-Mo),Shun(Chia-Tung... BMC Gastroenterol 2015-10-05

...PIK3CA mutation (exon 9 E545K) was identified only in LST (5/36, 13.9%). Mutations in KRAS, BRAF or PIK3CA occurred in a...

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