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Concordance of genomic alterations between primary and recurrent breast cance...

Meric-Bernstam(Funda),Frampton(Garrett M),... Mol Cancer Ther 2015-01-02

...PIK3CA, TP53, ARID1A, PTEN, AKT1, NF1, FBXW7, and FGFR3 and amplifications in MCL1, CCND1, FGFR1, MYC, IGF1R, MDM2, MDM4...

Characterization of the novel and specific PI3Kα inhibitor NVP-BYL719 and dev...

Fritsch(Christine),Huang(Alan),Chatenay-Ri... Mol Cancer Ther 2015-01-02

Somatic PIK3CA mutations are frequently found in solid tumors, raising the hypothesis that selective inhibition of PI3Kα...

Early gene expression changes in skeletal muscle from SOD1(G93A) amyotrophic ...

de Oliveira(Gabriela P),Maximino(Jessica R... Cell Mol Neurobiol 2015-02-12

...Pik3ca) and five down-regulated (Cd44, Eef2 k, Fzd2, Crebbp, Piki3r1) genes at 80 days. Also, protein-protein interactio...

PIK3CA gene alterations in bladder cancer are frequent and associate with red...

Dueñas(Marta),Martínez-Fernández(Mónica),G... Mol Carcinog 2015-08-25

...PIK3CA gene. However, the significance of PIK3CA gene alterations with respect to clinicopathological characteristics, a...

Loss of ARID1A expression and its relationship with PI3K-Akt pathway alterati...

Huang(Hsien-Neng),Lin(Ming-Chieh),Huang(We... Mod Pathol 2015-02-21

...PIK3CA) gene and fluorescence in situ hybridization for ZNF217 amplification. The correlations between ARID1A expression...

Genetic mutation screen in early non--small-cell lung cancer (NSCLC) specimen...

Bar(Jair),Damianovich(Maya),Hout Siloni(Go... Clin Lung Cancer 2015-05-21

...PIK3CA) was the gene to be found most commonly in tumors with co-mutations. Transversions were found mostly in KRAS gene...

Effectors of epidermal growth factor receptor pathway: the genetic profiling ...

Shen(Yinchen),Wang(Jianfei),Han(Xiaohong),... PLoS One 2015-03-02

...PIK3CA mutation and 4.19% (26/621) harbored a NRAS mutation. KRAS mutation coexisted with BRAF, PIK3CA and NRAS mutation...

PI3K mutations in breast cancer: prognostic and therapeutic implications.

Mukohara(Toru) Breast Cancer (Dove Med Press) 2015-06-01

...PIK3CA mutations are most frequently (∼30%) observed, along with protein loss of PTEN. Since the first discovery of PIK3...

Non-diethylstilbestrol exposed vaginal clear cell adenocarcinoma has a common...

Ikeda(Yuji),Oda(Katsutoshi),Aburatani(Hiro... Gynecol Oncol Rep 2015-06-17

...PIK3CA.•The genetic profile suggests that the carcinogenesis of PVCCA might have elements common with that of OCCA.

Cribriform-morular variant of papillary thyroid carcinoma: a study of 3 cases...

Kwon(Mi Jung),Rho(Young-Soo),Jeong(Jin Che... Hum Pathol 2015-10-06

...PIK3CA mutations. Using sequencing analyses and immunohistochemistry, we examined KRAS, BRAF, PIK3CA, and CTNNB1 mutatio...

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