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TP53 BRCA1 CRISPR single-cell cancer

Jang(Si-Hyong),Kim(Kyung-Ju),Oh(Mee-Hye),L... J Gastric Cancer 2016-07-19

...PIK3CA expression in gastric cancer and explored the relationships between the PIK3CA expression level and clinicopathol...

Yoo(Kwai Han),Kim(Nayoung K D),Kwon(Woo Il... Transl Oncol 2016-06-09

...PIK3CA mutations (N345K, E545K, and E521K). PDC models were successfully established in 27 of 40 samples (67.5%), includ...

Lorentzen(Jon A),Grzyb(Krzysztof),De Angel... Clin Med Insights Pathol 2016-09-22

...PIK3CA including the rarely studied KRAS exons 3 and 4 mutations. KRAS mutations were identified in 23.0% of the lesions...

Lin(Frank Y),Bergstrom(Katie),Person(Richa... Cold Spring Harb Mol Case Stud 2016-09-14

...PIK3CA (p.H1047R) and a germline pathogenic variant in PTPN11 (p.N308S) diagnostic for Noonan syndrome. The molecular la...

Liang(Haiqian),Wang(Renjie),Jin(Ying),Li(J... Am J Cancer Res 2016-09-20

...PIK3CA, an important member of PI3K/Akt signal pathway. These results demonstrate that the miR-422a/PIK3CA axis may cons...

Dey(Nandini),Sun(Yuliang),Carlson(Jennifer... Am J Cancer Res 2016-05-17

...PIK3CA mutated cell lines. BEZ235 alone and in combination with trastuzumab was tested on the tumor as well as stromal c...

Araujo(Luiz H),Lammers(Philip E),Matthews-... J Thorac Oncol 2016-09-15

...PIK3CA (0.8%), BRAF, NRAS, ERBB2, and AKT1 (0.4% each). ALK translocations were detected in two nonsquamous tumors (1.7%...

Ross(Jeffrey S),Ali(Siraj M),Wang(Kai),Kha... Breast Cancer Res Treat 2016-08-08

...PIK3CA (28 %), ERBB2 (26 %), FGFR1 (17 %), BRCA2 (15 %), and PTEN (15 %). In the TNBC subset of IBC, 8/19 (42 %) showed ...

Roy-Chowdhuri(Sinchita),de Melo Gagliato(D... Am J Clin Pathol 2016-02-02

...PIK3CA (31.7%), AKT1 (6%), and ATM (3.9%), with other mutations detected at a lower frequency. When stratified into clin...

Malanga(Donatella),De Marco(Carmela),Guerr... Oncotarget 2016-10-07

...PIK3CA or PTEN loss enhances formation of lung cancer spheroids (LCS), self-renewal, expression of stemness markers and ...

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