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TP53 BRCA1 CRISPR single-cell cancer

Tornesello(Maria Lina),Annunziata(Clorinda... J Transl Med 2016-04-12

...PIK3CA and alterations of p53 and PIK3CA AKT mTOR pathways are common events in several human cancers. We focused on the...

Campos(M),Kool(M M J),Daminet(S),Ducatelle... J Vet Intern Med 2016-04-18

...PIK3CA, PIK3CB, PDPK1, PTEN, AKT1, AKT2, COX-2, and CALCA. Mutation analysis was performed for known hotspots of RAS (N,...

Meriggi(Fausto),Vermi(William),Bertocchi(P... Rev Recent Clin Trials 2016-03-03

...PIK3CA pathways and is required to promote cell growth, differentiation, proliferation, and invasion. Cetuximab and pani...

Němeček(R),Svoboda(M),Slabý(O) Klin Onkol 2016-09-15

...PIK3CA oncogenes, inactivation of tumor suppressors PTEN and TP53, amplification of EGFR and HER2, and expression of epi...

Kim(Hong Jun),Lee(Suk-Young),Oh(Sang Cheul... Front Physiol 2016-05-31

...PIK3CA is an oncogenic mechanism in gastric cancer and colorectal cancer. Clinical trials with biologic agents that targ...

Xie(Jing),Lu(Xiongxiong),Wu(Xue),Lin(Xiaoy... Mol Genet Genomic Med 2016-06-01

...PIK3CA,TP53, and KRAS have been detected for indicating drug susceptibility and resistance in the cases of lung cancer.,...

Rodrik-Outmezguine(Vanessa S),Okaniwa(Masa... Nature 2016-07-06

...PIK3CA-AKT-mTOR pathway is one of the most commonly activated pathways in human cancers, which has led to the developmen...

Gao(Jie),Wu(Huanwen),Shi(Xiaohua),Huo(Zhen... Clin Lab 2016-06-09

...PIK3CA, and BRAF. The assays with the three platforms were compared and analyzed.,Compared with Sanger, NGS and QPCR ass...

Vogt(Peter K),Hart(Jonathan R),Yates(John ... Mol Cell Oncol 2016-06-16

...PIK3CA, the gene encoding the α isoform of class I phosphatidylinositol 3-kinase, induces extensive remodeling of the tr...

Chen(Wei),Liu(Bing-Yao),Zhang(Xiang),Zhao(... Arch Med Sci 2016-08-01

...PIK3CA, PTPN11 and PIK3R1 had a number of nodes greater than 10.,Transforming growth factor β1 might play a pivotal role...

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