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Combined effects and potential mechanisms of volatile organic compounds on ch...

Liang(B),Cao(M),Tan(H),Liu(Z),Liu(X) Toxicol Mech Methods 2026-05-22

...PIK3CA, PIK3CD, SRC, and AKT1 as candidate genes potentially relevant to the observed association, and enrichment analys...

Analytical and clinical validation of a novel CE-IVD kit for PIK3CA hotspot m...

Stergiopoulou(D),Smilkou(S),Tzanikou(E),Ka... J Liq Biopsy 2026-03-00

...PIK3CA kit, Pharmassist, Greece) for hotspot PIK3CA mutations (p.E542K, p.E545K, p.E545Q, p.H1047R) in liquid biopsy (LB...

Genomic Landscape and Therapeutic Implications of Metaplastic Breast Carcinom...

Suzuki(S),Seino(M),Sato(H),Kawai(M),Ogura(... Pharmaceuticals (Basel) 2026-02-12

...PIK3CA (46.0%) were the most prevalent genomic alterations in the MpBC cohort. Exploratory analysis suggested that PIK3C...

Gremlin-1 promotes leukemic survival via PI3K/AKT signaling in infant MLL-AF4...

Liu(X),Zhang(Y),Hua(S),Shao(X),Yin(L) Exp Hematol 2026-05-00

...PIK3CA attenuated GREM1-mediated survival effects. In a xenograft model based on pretreated leukemia cells, GREM1 neutra...

Exploring significant gender disparities in esophageal cancer risk: Insights ...

Cui(J),Zhang(R),Zhang(X),Zhang(Z),Li(M),He... Medicine (Baltimore) 2026-02-27

...PIK3CA proteins had no statistically significant impact on the survival of EC patients (PTEN: Log-rank P = .89, HR = 1.1...

Intimal sarcomas (ISarc) of the cardiac chambers (CC) of the heart and great ...

Zerdan(MB),Pavlick(D),Zaccarini(DJ),Ross(J... Cardiooncology 2026-02-28

...PIK3CA mutations were significantly more frequent in CC (20% vs 0%, P=0.007); ERBB3 mutations were infrequent and not si...

Signature-aware deep learning reveals distinct driver gene programs and mutat...

Zubair(M),Li(J),Qian(J) Comput Biol Chem 2026-08-00

...PIK3CA in COAD), and a model-derived driver burden stratifies survival. The code, trained weights, and processed feature...

Treatment of Vascular Anomalies With Sirolimus: An Updated Comprehensive Review.

Santos(PM),Loureiro(L),Pinelo(A),Machado(R... Port J Card Thorac Vasc Sur... 2026-05-10

...PIK3CA- related overgrowth spectrum (PROS) and PTEN hamartoma tumor syndrome (PHTS). However, sirolimus shows poor or ab...

A review of reviews of the prevalence of molecular biomarkers in vulvar cance...

Trozzi(R),Anderson(G),Romano(V),Iacobelli(... Gynecol Oncol 2026-07-00

...PIK3CA, HRAS, and FGFR3 variants emerged as potential therapeutic targets. Activating BRAF and c-KIT mutations were freq...

Association of genomic driver mutation, histologic subtype, and mTORC1 biomar...

Bhardwaj(S),Amaral(A),Dairo(O),Akbari(A),P... Hum Pathol 2026-09-00

...PIK3CA alterations (p = 0.02) with a nonsignificant trend for p-S6 (p = 0.15). There was no significant association of G...

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