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Ongusaha(Pat P),Ouchi(Toru),Kim(Kyung-Tae)... Oncogene 2003-07-02

...BRCA1 has been shown to enhance p53 transcription, whereas activated p53 represses BRCA1 transcription. To further under...

Maor(Sharon),Yosepovich(Ady),Papa(Moshe Z)... Cancer Lett 2008-01-03

...BRCA1 on IGF-IR levels, we infected the BRCA1-deficient HCC1937 cell line with a BRCA1-encoding adenoviral vector. Resul...

Clark(Serena L),Rodriguez(Ana M),Snyder(Ru... Comput Struct Biotechnol J 0000-00-00

...BRCA1 RING domain is responsible for the E3 ubiquitin ligase activity of BRCA1 and mediates interactions between BRCA1 a...

Abbott(D W),Thompson(M E),Robinson-Benion(... J Biol Chem 1999-07-15

...BRCA1 remains enigmatic. Here, we develop a human genetic system to study the role of BRCA1 in oxidative DNA damage. We ...

Bianco(T),Chenevix-Trench(G),Walsh(D C),Co... Carcinogenesis 2000-04-03

...BRCA1 in sporadic breast and ovarian cancers remains elusive. Direct involvement of BRCA1 in the development of breast a...

Sylvain(V),Lafarge(S),Bignon(Y J) Int J Oncol 2001-10-04

...Brca1 with those of a truncated Brca1 mutant in the ID-8 mouse ovarian cancer cell line after irradiation. We found that...

Hashizume(R),Fukuda(M),Maeda(I),Nishikawa(... J Biol Chem 2001-06-28

...BRCA1. Whereas individually BRCA1 and BARD1 have very low ubiquitin ligase activities in vitro, BRCA1 combined with BARD...

Kurebayashi(Junichi),Yamamoto(Yutaka),Kuro... Anticancer Res 2006-06-12

...BRCA1 functions differentially to modulate the chemosensitivity of cancer cells.,To clarify these findings, BRCA1 expres...

Nelson(Andrew C),Lyons(Traci R),Young(Chri... Mol Cell Endocrinol 2010-06-02

...BRCA1 result in breast and ovarian cancers suggests a functional relationship may exist between hormone signaling and BR...

Pathania(Shailja),Bade(Sangeeta),Le Guillo... Nat Commun 2015-12-08

...BRCA1 in the heterozygous state, we established a collection of primary human BRCA1(+/+) and BRCA1(mut/+) mammary epithe...