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miR-203 inhibits cell proliferation and promotes cisplatin induced cell death...

Lin(Jiong),Lin(Yao),Fan(Li),Kuang(Wei),Zhe... Biochem Biophys Res Commun 2016-09-06

...PIK3CA expression and Akt activation. Furthermore, miR-203 repressed PIK3CA expression through targeting the 3'UTR. Rest...

Malignancy of Cancers and Synthetic Lethal Interactions Associated With Mutat...

Wang(Xiaosheng),Zhang(Yue),Han(Ze-Guang),H... Medicine (Baltimore) 2016-07-21

...PIK3CA, and TP53 by comparison of their gene phenotype values in cancer cell lines with the relevant mutations and wild-...

Highlights from the 38th SABCS annual meeting, 8th - 12th December 2015, San ...

Cairns(Linda),Curigliano(Giuseppe) Ecancermedicalscience 2016-02-25

...PIK3CA, chemotherapy combinations for HER-2-positive disease, long-term outcomes of different surgeries for early-stage ...

Clinicopathologic Significance of HNF-1β, AIRD1A, and PIK3CA Expression in Ov...

Ye(Shuang),Yang(Jiaxin),You(Yan),Cao(Dongy... Medicine (Baltimore) 2016-07-15

...PIK3CA) mutations are common genetic changes in ovarian CCC. Hepatocyte nuclear factor-1β (HNF-1β) expression has been p...

Genomic analysis identifies new drivers and progression pathways in skin basa...

Bonilla(Ximena),Parmentier(Laurent),King(B... Nat Genet 2016-08-12

...PIK3CA (2%), and NRAS, KRAS or HRAS (2%), and loss-of-function and deleterious missense mutations were present in PTPN14...

MYC functions are specific in biological subtypes of breast cancer and confer...

Green(Andrew R),Aleskandarany(Mohammed A),... Br J Cancer 2016-08-24

...PIK3CA (P=0.009) and Ki67 (P<0.001). In contrast, in basal-like tumours, c-MYC showed positive association with Cyclin E...

Comprehensive analyses using next-generation sequencing and immunohistochemis...

Kuboki(Y),Yamashita(S),Niwa(T),Ushijima(T)... Ann Oncol 2016-09-22

...PIK3CA. On the other hand, most of the four RTK amplification cases (88.2%) were mutually exclusive with each amplificat...

Clinicopathological characteristics and mutation profiling in primary cutaneo...

Yaman(Banu),Akalin(Taner),Kandiloğlu(Gülşe... Am J Dermatopathol 2016-01-14

...PIK3CA, STK11, GNAQ, CTNNB1) were evaluated with real-time PCR-based PCR-Array through allele-specific amplification, an...

MAP2K1 (MEK1) Mutations Define a Distinct Subset of Lung Adenocarcinoma Assoc...

Arcila(Maria E),Drilon(Alexander),Sylveste... Clin Cancer Res 2016-01-26

...PIK3CA, and AKT. Additional cases were identified through a search of publically available cancer genomic datasets. Muta...

Development of siRNA payloads to target KRAS-mutant cancer.

Yuan(Tina L),Fellmann(Christof),Lee(Chih-S... Cancer Discov 2016-05-16

...PIK3CA/B). The customizable nature of Sensor siRNA payloads offers a universal platform for the combination target ident...

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