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TP53 BRCA1 CRISPR single-cell cancer

Mathew(Lijoy K),Huangyang(Peiwei),Mucaj(Ve... Sci Signal 2016-02-04

...PIK3CA and ARAF. However, increased RTK signaling usually activates negative feedback mechanisms to maintain homeostasis...

Vaca-Paniagua(Felipe),Alvarez-Gomez(Rosa M... PLoS One 2016-03-04

...PIK3CA, FOXM1), a repression of cell cycle control pathways (TP53, RB1), a deregulation of DNA-repair pathways, and alte...

Glaser(Gretchen),Weroha(S John),Becker(Mar... PLoS One 2016-02-03

...PIK3CA. In conclusion, ifosfamide/paclitaxel was superior to carboplatin/paclitaxel in this ovarian carcinosarcoma PDX a...

Bodnar(L),Stec(R),Cierniak(S),Synowiec(A),... Ann Oncol 2016-04-05

...PIK3CA gene variant rs6443624 (HR: AC + AA versus CC = 2.08, 95% CI 1 11-3.89, P = 0.0254). In multivariate analysis, it...

Yuan(Hua),Chen(Jiuan),Liu(Yiqiang),Ouyang(... Clin Cancer Res 2016-07-11

...PIK3CA mutations and response to neoadjuvant chemotherapy in women with primary breast cancer is not fully elucidated.,P...

Mohan(Suresh),Vander Broek(Robert),Shah(Su... Clin Cancer Res 2016-06-07

...PIK3CA, and sensitivity correlated with increased phospho-AKT(T308/S473). In resistant UMSCC-1 and -46 models, PF-384 in...

Xie(Chencheng),Lu(Huarui),Nomura(Alice),Ha... Mol Cancer 2016-03-24

...Pik3ca, ca-Akt, or dominant-negative (dn)-Foxo1 into apoptosis prone newborn murine retina with deleted Rb/p107 eliminat...

Bollig-Fischer(Aliccia),Michelhaugh(Sharon... Oncotarget 2016-05-12

...PIK3CA, NTRK1, GNAS, CTNNB1, and FGFR1. For a subset of the metastatic brain tumor samples (n = 4) we compared patient-m...

Bessette(Darrell C),Tilch(Erik),Seidens(Ta... PLoS One 2016-02-05

...PIK3CA H1047R mutation, that the MCF10CA1a cell line has acquired. Screening TNBC/basal-like breast cancer for EGFR muta...

Kajo(Karol),Vallová(Miroslava),Biró(Csaba)... Cesk Patol 2016-04-08

...PIK3CA, KRAS, CTNNB1 and TP53 genes, or leading to microsatellite instability. However, these changes are variably prese...

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