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TP53 BRCA1 CRISPR single-cell cancer

Shen(X),Kan(S),Hu(J),Li(M),Lu(G),Zhang(M),... Cell Death Dis 2016-11-09

...PIK3CA/AKT/mTOR signaling pathway. Accordingly, EMC6 knockdown in glioblastoma cells had the opposite effect; it promote...

Barlesi(Fabrice),Mazieres(Julien),Merlio(J... Lancet 2016-05-23

...PIK3CA mutations by 28 certified regional genetics centres in France. Patients were assessed consecutively during a 1-ye...

Lin(Lin),Zhang(Zhaoxu),Zhang(Wen),Wang(Lin... Int J Clin Exp Pathol 2016-10-13

...PIK3CA rs2699887 variants are associated with CRC susceptibility, clinicopathological parameters and clinical outcomes i...

Wan(Xiaoxiao),Li(Xian),Yang(Junyan),Lv(Wei... Int J Clin Exp Pathol 2016-10-11

...PIK3CA in oral squamous cell carcinoma (OSCC) and the association of gene polymorphisms of PIK3CA with OSCC in Chinese p...

Veija(Tuukka),Sarhadi(Virinder Kaur),Koljo... Cancer Genet 2016-06-23

...PIK3CA gene mutations, we found somatic mutations in the tyrosine kinase domain of the EGFR gene in a small proportion o...

Ross(Jeffrey S),Wang(Kai),Khaira(Depinder)... Cancer 2016-07-07

...PIK3CA) (20%), and ERBB2 (17%). FGFR3 GAs were diverse types and included 10% fusions. ERBB2 GAs were equally divided be...

Pongor(Lőrinc),Kormos(Máté),Hatzis(Christo... Genome Med 2016-05-19

...PIK3CA, and the top tumor suppressor genes included PHEX, TP53, GGA3, RGS22, PXDNL, ARFGEF1, BRCA2, CHD8, GCC2, and ARMC...

Subbiah(Vivek),Wagner(Michael J),McGuire(M... Oncotarget 2016-10-05

...PIK3CA mutation, CCNE1 amplification, and PTPRD mutation. Immunohistochemistry-based morphoproteomic analysis revealed c...

Chen(Dawei),Huang(Xuesong),Cai(Jie),Guo(Sh... Oncotarget 2016-09-22

...PIK3CA-E545G/K). Our data on an independent cohort support the recent clinical observation, but against the current prac...

Zabransky(Daniel J),Yankaskas(Christopher ... Proc Natl Acad Sci U S A 2016-02-26

...PIK3CA mutation, enhanced migratory features in vitro. However, the V777L mutation did not alter in vivo tumorigenicity ...

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