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TP53 BRCA1 CRISPR single-cell cancer

Harms(Paul W),Hovelson(Daniel H),Cani(Andi... Hum Pathol 2016-08-22

...PIK3CA-activating mutation reported in 1 case. We analyzed 5 porocarcinomas by next-generation sequencing using the DNA ...

Hembree(Timothy N),Teer(Jamie K),Hakam(Ard... Cancer Control 2016-10-31

...PIK3CA, CTNNB1, PTEN, FBXW7, TP53, and ERBB2; of these, TP53 was the most frequently mutated gene (6/9). In addition, AR...

Yang(Sherry X),Polley(Eric),Lipkowitz(Stan... Cancer Treat Rev 2016-08-19

...PIK3CA mutations and AKT activation by phosphorylation (pAKT) are often detected in many cancers and especially at high ...

Zangari(Andrea),Zaini(Johan),Gulìa(Caterin... Curr Genomics 2016-03-25

...PIK3CA, CTNNB1, FBXW7, IGF1R, PDGFRA, ERBB2/4, MET, BCOR. Malignant rhabdoid tumor (MRT) usually shows SMARCB1/INI1 alte...

Gunderson(Camille C),Rowland(Michelle R),W... Gynecol Oncol 2016-08-16

...PIK3CA (27%) were the most frequently noted mutations; however, molecular profiling resulted in identification of few ac...

Myers(Andrea P),Filiaci(Virginia L),Zhang(... Gynecol Oncol 2016-08-16

...PIK3CA, PIK3R1, KRAS, CTNNB1, AKT1, TSC1, TSC2, NF1, FBXW7) were explored.,Sequencing data was obtained from tumors of 5...

Penson(R T),Sales(E),Sullivan(L),Borger(D ... Gynecol Oncol 2016-08-16

...PIK3CA, PTEN, TP53).,Between 5/17/10 and 8/8/13, 249 pts consented to SNaPshot analysis. Median age 60 (29-84) yrs. Tumo...

Leroy(Cedric),Ramos(Pedro),Cornille(Karen)... Breast Cancer Res 2016-10-07

...PIK3CA mutant breast cancers. This provides a rationale for the combined targeting of p110α with IGF1R or p110β in patie...

Elwood(Peter C),Morgan(Gareth),Pickering(J... PLoS One 2016-08-25

...PIK3CA was present in about 20% of patients, and appeared to explain most of the reduction in colon cancer mortality by ...

Jones(Nathaniel L),Xiu(Joanne),Reddy(Sande... Gynecol Oncol 2016-02-01

Therapeutic options are limited for uterine serous carcinoma (USC). TP53, PIK3CA, FBXW7, and ERBB mutations, as well as ...

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