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Ries(AG),Barry(KK),Thiessen(A),Plunk(MR),K... Pediatr Dermatol 2026-00-00

...PIK3CA variants are well-documented and are classified within the PIK3CA-related overgrowth spectrum (PROS), yet PIK3CA-...

Zhong(H),Liu(T),Bai(L),Li(J),Song(M),Zhou(... Sichuan Da Xue Xue Bao Yi X... 2026-03-20

...PIK3CA (12.73%). TP53 mutations were associated with T4 stage (P = 0.028) and diffuse-type gastric cancer (P = 0.008). C...

Zhao(S),Fan(X),Jia(X),Xu(H),Xia(Y),Lu(B),Y... Eur J Med Chem 2026-08-05

...PIK3CA mutant protein. The development of allosteric PI3Kα inhibitors provides new ideas for overcoming these problems. ...

Xu(L),Zhao(X),Meng(X),Chen(J),Chen(P) Anal Chem 2026-05-05

...PIK3CA E542K mutation. A pivotal discovery of this study is that activated Cas12a efficiently cleaves metal ion-mediated...

Jani(CT),Tran(E),Zhang(N),Tsai(J),Dong(J),... Clin Cancer Res 2026-05-15

...PIK3CA (9.4%/15.9%), and EGFR (9.6%/14.6%). All treatment cohorts showed a significant increase in mutation burden after...

Yao(YC),He(MM),Wang(M),Mo(YX),Zhao(Q),Jin(... Gastroenterol Rep (Oxf) 2026-02-00

...PIK3CA (overall survival: 15.5 vs 5.7 months) were associated with shorter survival time. ctDNA dynamics appeared relate...

Zhang(J),Pei(J),Hao(G),Meng(Y),Li(F),Xu(H)... Medicine (Baltimore) 2026-05-15

...PIK3CA mutation in the patient. The patient's condition was effectively controlled after treatment with PI3K inhibitors....

Jhaveri(K),Rugo(HS),Cortés(J),Oliveira(M),... Clin Cancer Res 2026-08-14

...PIK3CA/AKT1/PTEN tumor alterations. Next-generation sequencing (NGS) is commonly used to identify patients with PIK3CA/A...

Barraud(S),Roussel-Simonin(C),Pautier(P),I... Br J Cancer 2026-08-00

...PIK3CA mutations were significantly more frequent in LTR, while STK11 alterations were enriched in NLTR. Durable respons...

Chen(WY),Chen(WC),Tan(PH),Chen(YM),Chuang(... Virchows Arch 2026-05-19

...PIK3CA and KRAS, particularly in case #1. Of note, the case #1 PIK3CA p.Q546K alteration was concordantly identified in ...