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TP53 BRCA1 CRISPR single-cell cancer

Khemlina(Galina),Ikeda(Sadakatsu),Kurzrock... Cancer Treat Rev 2016-01-26

...PIK3CA. Some of these alterations are actionable by drugs available in the clinic. In addition, it was recently shown th...

Ferrándiz-Pulido(Carla),Hernández-Losa(Jav... Genes Chromosomes Cancer 2016-05-09

...PIK3CA, KRAS, HRAS, NRAS, and PDGFA genes. Somatic mutations in the PIK3CA gene or RAS family genes were neither associa...

Carethers(John M),Jung(Barbara H) Gastroenterology 2016-01-11

...PIK3CA and mutation and loss of heterozygosity of tumor suppressor genes, such as APC and TP53; (3) CpG island methylato...

Arqués(Oriol),Chicote(Irene),Puig(Isabel),... Clin Cancer Res 2016-10-25

...PIK3CA) did not.,High nuclear β-catenin content independently predicts resistance to PI3K and AKT inhibitors. Combined t...

Haley(Lisa),Tseng(Li-Hui),Zheng(Gang),Dudl... Mod Pathol 2016-08-18

...PIK3CA genes by a clinically validated next-generation sequencing assay in 310 colorectal cancer specimens. Tumor cellul...

Chatziandreou(Ilenia),Tsioli(Panagiota),Sa... PLoS One 2016-05-05

...PIK3CA, MET-gene copy number and ALK rearrangements in a large cohort of 956 NSCLC patients of Hellenic origin using hig...

Karlsson(Elin),Veenstra(Cynthia),Emin(Shad... Breast Cancer Res Treat 2016-05-05

...PIK3CA mutations, have been shown frequently especially in the luminal breast cancer subtypes, suggesting a cross-talk b...

Röcken(Christoph),Behrens(Hans-Michael),Bö... J Clin Pathol 2016-04-11

...PIK3CA mutation. No significant difference was found in the overall survival between RHOA mutant and wildtype GCs. Our s...

Kato(Shumei),Elkin(Sheryl K),Schwaederle(M... Oncotarget 2016-07-25

...PIK3CA, PIK3R1, PTEN or AKT1/3) (28/117 [23.9%]). In multivariate analysis, statistically significant co-existing aberra...

Mahdi(Haider),Xiu(Joanne),Reddy(Sandeep K)... J Surg Oncol 2016-01-18

...PIK3CA (29% vs. 2%, P < 0.001), FBXW7 (12% vs. 1%, P < 0.001), KRAS (9% vs. 5%, P < 0.001) PTEN (7% vs. 1%, P < 0.001), ...

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