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TP53 BRCA1 CRISPR single-cell cancer

Karlsson(Elin),Veenstra(Cynthia),Emin(Shad... Breast Cancer Res Treat 2016-05-05

...PIK3CA mutations, have been shown frequently especially in the luminal breast cancer subtypes, suggesting a cross-talk b...

Tian(Linlu),Li(Lixian),Xing(Wenjing),Li(Ru... Sci Rep 2016-06-30

...PIK3CA mediated Rac1 activation. Together, these data reveals a novel molecular mechanism that involved in melanoma meta...

Haley(Lisa),Tseng(Li-Hui),Zheng(Gang),Dudl... Mod Pathol 2016-08-18

...PIK3CA genes by a clinically validated next-generation sequencing assay in 310 colorectal cancer specimens. Tumor cellul...

Khemlina(Galina),Ikeda(Sadakatsu),Kurzrock... Cancer Treat Rev 2016-01-26

...PIK3CA. Some of these alterations are actionable by drugs available in the clinic. In addition, it was recently shown th...

Liang(Min),Shi(Boyun),Liu(Jifang),He(Lu),Y... Drug Des Devel Ther 2016-04-18

...PIK3CA in 107 gastric cancer specimens and their adjacent nontumorous tissues. PIK3CA siRNA was synthesized and transfec...

Klempner(Samuel J),Bazhenova(Lyudmila A),B... Lung Cancer 2016-05-05

...PIK3CA mutation, epithelial-mesenchymal transition (EMT), small cell transformation have also been identified. However o...

Dam(Claus),Lund-Rasmussen(Vera),Pløen(John... Dan Med J 2016-04-13

...PIK3CA genes were also treated with panitumumab. Before and after treatment, we measured the tumour diameter in two diff...

Salgado(Roberto),Denkert(Carsten),Campbell... JAMA Oncol 2016-04-04

...PIK3CA genotype.,Of the 455 patients, 387 (85.1%) tumor samples were used for the present analysis. The median (interqua...

Korkola(James E),Collisson(Eric A),Heiser(... PLoS One 2016-04-27

...PIK3CA(mut )sequences were similar to those observed in HER2(+)/PIK3CA(mut) cell lines but not in HER2(+)/PIK3CA(wt) cel...

Mima(Kosuke),Sukawa(Yasutaka),Nishihara(Re... JAMA Oncol 2016-03-31

...PIK3CA mutation status. We adjusted the 2-sided α level to .013 for multiple hypothesis testing.,Densities of CD3+, CD8+...

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