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TP53 BRCA1 CRISPR single-cell cancer

Park(Ji Hyun),Ryu(Min-Hee),Park(Young Soo)... BMC Cancer 2016-01-22

...PIK3CA hotspot mutation and pS6 overexpression in the primary tumor. After two cycles of everolimus re-treatment, the ov...

Birgisson(Helgi),Edlund(Karolina),Wallin(U... BMC Cancer 2016-01-22

...PIK3CA mutations, microsatellite instability (MSI), and average DNA copy number, in connection with tumour dissemination...

Ye(Hua),Zhang(Jing),Wang(Jun),Gao(Yanyan),... Arthritis Res Ther 2016-01-08

...PIK3CA) were involved in STAT3 (signal transducer and activator of transcription 3) signaling, and three genes (CBL, KLF...

Ali(Siraj M),Sanford(Eric M),Klempner(Samu... Oncologist 2016-04-11

...PIK3CA (8.6%), MLL2 (6.9%), FGFR2 (6.0%), and MET (6.0%). Receptor tyrosine kinase genomic alterations were detected in ...

Bosch(Ana),Li(Zhiqiang),Bergamaschi(Anna),... Sci Transl Med 2016-01-12

Activating mutations of PIK3CA are the most frequent genomic alterations in estrogen receptor (ER)-positive breast tumor...

McGranahan(Nicholas),Favero(Francesco),de ... Sci Transl Med 2016-01-12

...PIK3CA (E545K), EGFR (L858R), and KRAS (G12D), which may compromise the efficacy of targeted therapy approaches. More th...

Moulder(S),Helgason(T),Janku(F),Wheler(J),... Ann Oncol 2016-04-05

...PIK3CA/Akt/mTOR axis: PIK3CA mutation = 2; PTEN loss = 1; NF2 aberration = 1.,DAT has activity in MpBCs including comple...

Guerini-Rocco(Elena),Hodi(Zsolt),Piscuogli... J Pathol 2016-06-06

...PIK3CA, MTOR, CTNNB1, BRCA1, ERBB4, ERBB3, INPP4B, and FGFR2. Copy number alteration analysis revealed complex patterns ...

Severson(Tesa M),Peeters(Justine),Majewski... Mol Oncol 2016-08-15

...PIK3CA was assessed. Gene expression and mutation frequency in BRCA1-like and non-BRCA1-like tumors were compared. Multi...

Despierre(Evelyn),Vergote(Ignace),Anderson... Target Oncol 2016-10-06

...PIK3CA, EGFR, and PTEN (in 7.5 % of patients), of which the most frequent were in KRAS and PIK3CA. EGFR mutations occurr...

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