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BRCA1-like signature in triple negative breast cancer: Molecular and clinical...

Severson(Tesa M),Peeters(Justine),Majewski... Mol Oncol 2016-08-15

...PIK3CA was assessed. Gene expression and mutation frequency in BRCA1-like and non-BRCA1-like tumors were compared. Multi...

Epidermal Growth Factor Receptor (EGFR) Pathway Biomarkers in the Randomized ...

Despierre(Evelyn),Vergote(Ignace),Anderson... Target Oncol 2016-10-06

...PIK3CA, EGFR, and PTEN (in 7.5 % of patients), of which the most frequent were in KRAS and PIK3CA. EGFR mutations occurr...

Identification of E545k mutation in plasma from a PIK3CA wild-type metastatic...

Romero(Atocha),Acosta-Eyzaguirre(Daniel),S... Transl Res 2016-03-21

...PIK3CA wild-type primary tumor in which the PIK3CA E545K mutation was identified in both the circulating-free DNA obtain...

Inhibition of PI3K Pathway Reduces Invasiveness and Epithelial-to-Mesenchymal...

Bonelli(Mara A),Cavazzoni(Andrea),Saccani(... Mol Cancer Ther 2016-05-05

...PIK3CA-mutated SQCLC cells and in newly generated clones carrying PIK3CA alterations, as well as in a xenograft model. P...

Feasibility of Large-Scale Genomic Testing to Facilitate Enrollment Onto Geno...

Meric-Bernstam(Funda),Brusco(Lauren),Shaw(... J Clin Oncol 2016-04-29

...PIK3CA/AKT1/PTEN/BRAF mutations that returned for therapy, 116 (50%) received a genotype-matched drug. Forty patients (1...

[Molecular analysis of sporadic colon cancer].

Hurtado(Claudia),Wielandt(Ana María),Zárat... Rev Med Chil 2016-04-21

...PIK3CA (E542K, E545D, E545K, Q546E, H1047R). BRAF mutations alone or in combination with PIK3CA mutations were observed ...

PIK3CA Somatic Mutation Status in Relation to Patient and Tumor Factors in Ra...

Phipps(Amanda I),Ahnen(Dennis J),Cheng(Ion... Cancer Epidemiol Biomarkers... 2016-03-31

...PIK3CA). We evaluated the relationship of PIK3CA mutation status in colorectal cancer with race/ethnicity, colorectal ca...

Epidermal growth factor receptor pathway mutation and expression profiles in ...

Bumrungthai(Sureewan),Munjal(Kavita),Nande... J Transl Med 2016-03-17

...PIK3CA mutations by PNA-clamp real-time PCR. Immunohistochemistry (IHC) was performed for EGFR, PIK3CA, PTEN, phospho-AK...

A combination of molecular markers and clinical features improve the classifi...

Springer(Simeon),Wang(Yuxuan),Dal Molin(Ma... Gastroenterology 2016-04-07

...PIK3CA, RNF43, SMAD4, TP53, and VHL); to identify loss of heterozygozity at CDKN2A, RNF43, SMAD4, TP53, and VHL tumor su...

De novo resistance biomarkers to anti-HER2 therapies in HER2-positive breast ...

Madrid-Paredes(Adela),Cañadas-Garre(Marisa... Pharmacogenomics 2016-06-16

...PIK3CA or AKT1, cannot be fully established yet.

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