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Contribution of Beta-HPV Infection and UV Damage to Rapid-Onset Cutaneous Squ...

Cohen(Daniel N),Lawson(Steven K),Shaver(Aa... Clin Cancer Res 2016-02-22

...PIK3CA, CKIT, ALK, and EGFR mutations also detected.,We examined clinical, histopathologic, viral, and genetic parameter...

Refining prognosis and identifying targetable pathways for high-risk endometr...

Stelloo(Ellen),Bosse(Tjalling),Nout(Remi A... Mod Pathol 2016-03-25

...PIK3CA, PPP2R1A, and PTEN) and protein expression of ER, PR, PTEN, and ARID1a was analyzed. Rates of distant metastasis,...

Genomic alterations in head and neck squamous cell carcinoma determined by ca...

Chung(C H),Guthrie(V B),Masica(D L),Tokhei... Ann Oncol 2016-05-13

...PIK3CA and PTEN in HPV-positive tumors and TP53 and CDKN2A/B in HPV-negative tumors. In the pathway analysis, the PI3K p...

AKT1 E17K in Colorectal Carcinoma Is Associated with BRAF V600E but Not MSI-H...

Hechtman(Jaclyn F),Sadowska(Justyna),Huse(... Mol Cancer Res 2016-03-18

...PIK3CA-mutated colorectal carcinoma are described in detail. Interestingly, in comparison with PIK3CA mutants, AKT1 E17K...

Molecular landscape of pancreatic cancer: implications for current clinical t...

Heestand(Gregory M),Kurzrock(Razelle) Oncotarget 2016-01-12

...PIK3CA, and BRAF. In the era of tumor profiling, these aberrations may provide an opportunity for new therapeutic approa...

Driver gene mutations of non-small-cell lung cancer are rare in primary carci...

Armengol(Gemma),Sarhadi(Virinder Kaur),Rön... Lung 2016-03-21

...PIK3CA, and KRAS. All these mutations were confirmed as somatic and are previously known mutations. In summary, mutation...

Deciphering the impact of somatic mutations in exon 20 and exon 9 of PIK3CA g...

Sudhakar(N),Priya Doss(C George),Thirumal ... J Biomol Struct Dyn 2016-10-07

...PIK3CA gene in South Indian population. Genomic DNA was isolated and amplified for PIK3CA gene, followed by direct seque...

Comprehensive analysis of targetable oncogenic mutations in chinese cervical ...

Xiang(Libing),Li(Jiajia),Jiang(Wei),Shen(X... Oncotarget 2016-03-01

...PIK3CA (12.3%), KRAS (5.3%), HER2 (4.2%), FGFR3-TACC3 fusions (3.9%), PTEN (2.8%), FGFR2 (1.8%), FGFR3 (0.7%), NRAS (0.7...

Molecular Characteristics of Basaloid Squamous Cell Carcinoma of the Esophagu...

Baba(Yoshifumi),Ishimoto(Takatsugu),Harada... Ann Surg Oncol 2016-06-06

...PIK3CA mutation, all BSCC cases were wild-type for PIK3CA (p = 0.002), and there were no differences in p53 expression b...

Are acinic cell carcinomas of the breast and salivary glands distinct disease...

Piscuoglio(Salvatore),Hodi(Zsolt),Katabi(N... Histopathology 2016-07-20

...PIK3CA (10%). We sought to define whether breast AcCCs would harbour TP53 and PIK3CA somatic mutations, and if so, wheth...

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