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TP53 BRCA1 CRISPR single-cell cancer

Madrid-Paredes(Adela),Cañadas-Garre(Marisa... Pharmacogenomics 2016-06-16

...PIK3CA or AKT1, cannot be fully established yet.

Kavuri(Shyam M),Jain(Naveen),Galimi(France... Cancer Discov 2016-05-05

...PIK3CA) wild-type (WT) colorectal cancer patient-derived xenografts (PDX) identified 4 PDXs with HER2 mutations. HER2-ta...

Mahdi(Haider),Xiu(Joanne),Reddy(Sandeep K)... J Surg Oncol 2016-01-18

...PIK3CA (29% vs. 2%, P < 0.001), FBXW7 (12% vs. 1%, P < 0.001), KRAS (9% vs. 5%, P < 0.001) PTEN (7% vs. 1%, P < 0.001), ...

Abba(Martin C),Gong(Ting),Lu(Yue),Lee(Jaeh... Cancer Res 2016-01-04

...PIK3CA (21% of cases), TP53 (17%), GATA3 (7%), MLL3 (7%) and single cases of mutations affecting CDH1, MAP2K4, TBX3, NF1...

Spaans(Vivian M),Trietsch(Marjolijn D),Pet... PLoS One 2016-05-13

...PIK3CA (20%) and KRAS (7%). PIK3CA mutations occurred more frequently in SCC than AC (25% vs. 11%, P=0.025), whereas KRA...

Haroche(Julien),Cohen-Aubart(Fleur),Charlo... Expert Rev Clin Immunol 2016-05-31

...PIK3CA) have recently been described. These mutations should lead to a new classification of histiocytic disorders such ...

Shim(Hyo Sup),Kenudson(Mari-),Zheng(Zongli... J Thorac Oncol 2016-05-19

...PIK3CA mutations. Unexpectedly, we found only two cases with TP53 mutation, which is much lower than observed in lung ad...

Mitsuhashi(Kei),Yamamoto(Itaru),Kurihara(H... Oncotarget 2016-09-22

...PIK3CA or any microsatellite instability (MSI); however, we did observe CpG island methylator phenotype (CIMP) positivit...

Le Rolle(Anne-France),Klempner(Samuel J),G... Oncotarget 2016-08-10

...PIK3CA or other fusion tyrosine kinases. Multiple RET kinase inhibitors were cytotoxic to RET fusion kinase positive can...

Springer(Simeon),Wang(Yuxuan),Dal Molin(Ma... Gastroenterology 2016-04-07

...PIK3CA, RNF43, SMAD4, TP53, and VHL); to identify loss of heterozygozity at CDKN2A, RNF43, SMAD4, TP53, and VHL tumor su...

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