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TP53 BRCA1 CRISPR single-cell cancer

Encinas(Giselly),Maistro(Simone),Pasini(Fá... Rev Assoc Med Bras (1992) 2016-04-25

...PIK3CA wild type tumor was associated with early onset, not confirmed in binary regression with estrogen receptor (ER) s...

Wang(Y L),Dai(X),Li(Y D),Cheng(R X),Deng(B... Genet Mol Res 2016-09-02

...PIK3CA, BRAF, and KRAS in Chinese breast cancer patients. In this study, we conducted sequence analysis of PIK3CA, BRAF,...

Vollbrecht(Claudia),Werner(Robert),Walter(... Br J Cancer 2016-05-10

...PIK3CA-mutated patients with high-grade tumours showed a reduced overall survival (P=0.040) and the mutation frequency o...

Ross(Jeffrey S),Wang(Kai),Khaira(Depinder)... Cancer 2016-07-07

...PIK3CA) (20%), and ERBB2 (17%). FGFR3 GAs were diverse types and included 10% fusions. ERBB2 GAs were equally divided be...

Jesinghaus(Moritz),Pfarr(Nicole),Kloor(Mat... Genes Chromosomes Cancer 2016-10-06

...PIK3CA, and TGFBR2, most of them being subclonal events. Lastly, we detected four cases (17%) with microsatellite instab...

Allen(Carl E),Parsons(D Williams) Hematology Am Soc Hematol E... 2016-10-14

...PIK3CA have also been described. The heterogeneous clinical manifestations of these disorders may therefore be the cumul...

Limaye(Nisha),Kangas(Jaakko),Mendola(Anton... Am J Hum Genet 2016-03-22

...PIK3CA, the gene encoding the catalytic p110α subunit of PI3K, cause 54% (27 out of 50) of VMs with no detected TEK muta...

Huo(Zhen),Wu(Huanwen),Li(Ji),Li(Shanqing),... PLoS One 2016-06-28

...PIK3CA, PDGFRA, and DDR2 genes were carried out using next-generation sequencing (NGS), Sanger sequencing, and quantitat...

Green(Shon),Trejo(Christy L),McMahon(Marti... Cancer Res 2016-04-26

...PIK3CA(H1047R) mutation. PIK3CA(H1047R) expression alone failed to promote tumor formation, but dramatically enhanced tu...

Roy(Achira),Skibo(Jonathan),Kalume(Franck)... Elife 2016-08-22

Mutations in the catalytic subunit of phosphoinositide 3-kinase (PIK3CA) and other PI3K-AKT pathway components have been...

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