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TP53 BRCA1 CRISPR single-cell cancer

Kuboki(Y),Yamashita(S),Niwa(T),Ushijima(T)... Ann Oncol 2016-09-22

...PIK3CA. On the other hand, most of the four RTK amplification cases (88.2%) were mutually exclusive with each amplificat...

Chang(Shih-Ching),Lin(Pei-Ching),Lin(Jen-K... Ann Surg Oncol 2016-11-10

...PIK3CA (179, 14.3%); 137 (11.0%) cancers had high microsatellite instability (MSI). Women had significantly higher high ...

Serrano(César),Romagosa(Cleofé),Hernández-... Cancer 2016-06-06

...PIK3CA) oncogenic mutations was performed as well.,Critical lymph nodes within the RAS/MAPK and PI3K/mTOR pathways were ...

Al-Rohil(Rami N),Tarasen(Ashley J),Carlson... Cancer 2016-05-13

...PIK3CA) (6%); cyclin D1 (CCND1) (6%); epidermal growth factor receptor (EGFR) (5%); and F-box and WD repeat domain conta...

Malanga(Donatella),De Marco(Carmela),Guerr... Oncotarget 2016-10-07

...PIK3CA or PTEN loss enhances formation of lung cancer spheroids (LCS), self-renewal, expression of stemness markers and ...

Kim(Seung Tae),Ahn(Tae Jin),Lee(Eunjin),Do... BMC Cancer 2016-06-27

...PIK3CA and profiled comprehensively the expression of 522 kinase genes.,BRAF mutation was detected in 5.1 % (3/58) of pa...

Yu(Yi),Savage(Ronald E),Eathiraj(Sudharsha... PLoS One 2016-06-27

...PIK3CA/PIK3R1 mutations compared to those with wt-PIK3CA/PIK3R1 or PTEN mutations. For both ARQ 092 and ARQ 751, PIK3CA/...

Chen(Shao-Jun) Chin J Nat Med 2016-08-01

...PIK3CA), and mitogen-activated protein kinase kinase 1 (MAP2K1), whereas analysis of the STITCH-constructed network reve...

Best(Myron G),Sol(Nik),Kooi(Irsan),Tannous... Cancer Cell 2016-04-04

...PIK3CA tumors were accurately distinguished using surrogate TEP mRNA profiles. Our results indicate that blood platelets...

Inoue(Yusuke),Matsuura(Shun),Kurabe(Nobuya... J Thorac Oncol 2016-09-20

...PIK3CA amplification in Japanese patients with non-small-cell lung cancer (NSCLC).,The copy numbers of the seven above-m...

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