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TP53 BRCA1 CRISPR single-cell cancer

Bonelli(Mara A),Cavazzoni(Andrea),Saccani(... Mol Cancer Ther 2016-05-05

...PIK3CA-mutated SQCLC cells and in newly generated clones carrying PIK3CA alterations, as well as in a xenograft model. P...

Meric-Bernstam(Funda),Brusco(Lauren),Shaw(... J Clin Oncol 2016-04-29

...PIK3CA/AKT1/PTEN/BRAF mutations that returned for therapy, 116 (50%) received a genotype-matched drug. Forty patients (1...

Chen(Shang-Wen),Lin(Chien-Yu),Ho(Cheng-Man... Clin Nucl Med 2016-02-09

...PIK3CA. Mann-Whitney U test and logistic regression analysis were carried out for this analysis.,Genetic alterations in ...

Pelosi(Giuseppe),Fabbri(Alessandra),Papott... J Thorac Oncol 2016-09-20

...PIK3CA, PTPN11, RET, SMAD4, SMO, STK11, or TP53 mutations in keeping with ADC lineage, whereas three tumors showing TTF1...

Bronte(Giuseppe),Silvestris(Nicola),Castig... Oncotarget 2016-07-19

...PIK3CA mutations, PTEN loss, AREG and EREG expression, and HER-2 amplification have already been identified to select re...

Llovet(Patricia),Sastre(Javier),Ortega(Jul... Mol Diagn Ther 2016-09-05

...PIK3CA, phosphatase and tensin homolog (PTEN), amphiregulin (AREG), and epiregulin (EREG)] in 105 patients with mCRC KRA...

Butler(Timothy M),Johnson-Camacho(Katherin... PLoS One 2016-05-11

...PIK3CA mutation (H1047R) which was clonal in the primary tumor, but completely absent from either the metastasis or cfDN...

Clynick(Britt),Tabone(Tania),Fuller(Kathry... J Mol Diagn 2016-07-20

...PIK3CA, APC, and HRAS), which was distinct to that seen in squamous cell carcinomas (FGFR3, CDKN2A, and STK11). We have ...

van Kessel(Kim E M),Van Neste(Leander),Lur... J Urol 2016-06-27

...PIK3CA, FGFR3 (fibroblast growth factor receptor 3), HRAS, KRAS and NRAS.,The combination of TWIST1, ONECUT2 (2 loci) an...

Black(Jonathan D),Lopez(Salvatore),Cocco(E... Br J Cancer 2016-01-04

...PIK3CA-mutations. Four HER2/neu-amplified USC (2-harbouring wild-type-PIK3CA-genes and 2-harbouring oncogenic-PIK3CA-mut...

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