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TP53 BRCA1 CRISPR single-cell cancer

Lo Iacono(Marco),Monica(Valentina),Righi(L... J Thorac Oncol 2016-03-08

...PIK3CA, STK11, and NF2). PIK3CA:c.1173A>G mutation, STK11:rs2075606 (T>C), or TP53:rs1042522 (Pro/Pro) was significantly...

Jimeno(A),Shirai(K),Choi(M),Laskin(J),Koch... Ann Oncol 2016-08-18

...PIK3CA mutations were observed in 17% of the cases assessed, and PTEN loss was infrequently observed.,The addition of PX...

Wu(Chunyan),Zhao(Chao),Yang(Yang),He(Yayi)... J Thorac Oncol 2016-03-21

...PIK3CA together with fusions in ALK, ROS1, and RET.,From 35 patients, a total of 72 lesions (60 were GGNs) were analyzed...

Grünwald(V),Keilholz(U),Boehm(A),Guntinas-... Ann Oncol 2016-08-18

...PIK3CA mutations, and HPV status. Archived tumor tissue was analyzed for DNA sequence.,A total of 40 patients were eligi...

Chao(Angel),Lai(Chyong-Huey),Lee(Yun-Shien... BMC Cancer 2016-01-25

...PIK3CA in the endometrial cancer, and a somatic mutation of GNA11 and JAK3 in the PMM. Large-scale genomic amplification...

Li(Yvonne Y),Hanna(Glenn J),Laga(Alvaro C)... Clin Cancer Res 2016-02-04

...PIK3CA, FGFR3, BRAF, and EGFR, similar to those reported in SCCs of the lung and head and neck, suggesting that clinical...

Adi Harel(S),Bossel Ben-Moshe(N),Aylon(Y),... Cell Death Differ 2016-05-02

...PIK3CA mRNA directly. Our results imply that miR-512 and miR-373 exert cell-autonomous and non-autonomous tumor-suppress...

Betge(Johannes),Kerr(Grainne),Miersch(Thil... PLoS One 2016-04-21

...PIK3CA (3) and KRAS (2). A high concordance of FFPE and paired frozen tissue samples was observed in ten matched samples...

Pazarentzos(E),Giannikopoulos(P),Hrustanov... Oncogene 2016-08-01

...PIK3CA and PTEN are known to drive PI3K pathway activation and cancer growth, the significance of somatic mutations in o...

Guerini-Rocco(Elena),Hodi(Zsolt),Piscuogli... J Pathol 2016-06-06

...PIK3CA, MTOR, CTNNB1, BRCA1, ERBB4, ERBB3, INPP4B, and FGFR2. Copy number alteration analysis revealed complex patterns ...

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