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Roles of genetic variants in the PI3K/PTEN pathways in susceptibility to colo...

Lin(Lin),Zhang(Zhaoxu),Zhang(Wen),Wang(Lin... Int J Clin Exp Pathol 2016-10-13

...PIK3CA rs2699887 variants are associated with CRC susceptibility, clinicopathological parameters and clinical outcomes i...

Genetic association between PIK3CA gene and oral squamous cell carcinoma: a c...

Wan(Xiaoxiao),Li(Xian),Yang(Junyan),Lv(Wei... Int J Clin Exp Pathol 2016-10-11

...PIK3CA in oral squamous cell carcinoma (OSCC) and the association of gene polymorphisms of PIK3CA with OSCC in Chinese p...

Spatial genomic heterogeneity in diffuse intrinsic pontine and midline high-g...

Hoffman(Lindsey M),DeWire(Mariko),Ryall(Sc... Acta Neuropathol Commun 2016-10-14

...PIK3CA (n = 2), FGFR1 (n = 2), and MET (n = 1) were also intra-tumorally conserved. ACVR1 was co-mutated with HIST1H3B (...

Hotspot mutations in polyomavirus positive and negative Merkel cell carcinoma...

Veija(Tuukka),Sarhadi(Virinder Kaur),Koljo... Cancer Genet 2016-06-23

...PIK3CA gene mutations, we found somatic mutations in the tyrosine kinase domain of the EGFR gene in a small proportion o...

Targeting the PI3K signaling pathway in KRAS mutant colon cancer.

Hong(Suntaek),Kim(SoYoung),Kim(Hye Youn),K... Cancer Med 2016-10-20

...PIK3CA), but it is unknown whether BKM120 can reverse cetuximab resistance in KRAS mutant CRC. Human CRC cell lines with...

Three Rounds of External Quality Assessment in France to Evaluate the Perform...

Dequeker(Elisabeth M C),Keppens(Cleo),Egel... J Mol Diagn 2016-10-31

...PIK3CA, microsatellite instability) and non-small cell lung cancer (EGFR, KRAS, BRAF, PIK3CA, ERBB2), and they represent...

Genome Sequencing of Autism-Affected Families Reveals Disruption of Putative ...

Turner(Tychele N),Hormozdiari(Fereydoun),D... Am J Hum Genet 2016-05-11

...PIK3CA). Our results suggest that the detection of smaller, often multiple CNVs affecting putative regulatory elements m...

Multi-Scale Genomic, Transcriptomic and Proteomic Analysis of Colorectal Canc...

Briffa(Romina),Um(Inhwa),Faratian(Dana),Zh... PLoS One 2016-06-28

...PIK3CA, MYC, SMO, TRIB1, FZD1, and BRCA2, while frequently lost regions contained FHIT and MACROD2. TRIB1 was selected f...

Prognostic and Therapeutic Markers in Chordomas: A Study of 287 Tumors.

Tauziéde-Espariat(Arnault),Bresson(Damien)... J Neuropathol Exp Neurol 2016-08-09

...PIK3CA mutations were analyzed. On univariate analysis, the results confirm surgery as the best treatment, as judged by ...

Particular molecular and ultrastructural aspects in invasive mammary carcinom...

Mihalcea(Corina Elena),Moroşanu(Ana Maria)... Rom J Morphol Embryol 2016-11-07

...PIK3CA, p110α catalytic subunit of PI3K. Our study confirms the high prevalence of PIK3CA mutations in breast cancer. In...

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