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TP53 BRCA1 CRISPR single-cell cancer

Feldman(Darren R) Curr Opin Oncol 2016-02-17

...PIK3CA-AKT and RAS pathways. Circulating tumour cells and circulating microRNAs are potential new biomarkers. In clinica...

Ekizoglu(S),Dogan(S),Ulker(D),Seven(D),Goz... Clin Otolaryngol 2016-10-18

...PIK3CA, PIK3R1 and AKT1 genes were analysed by direct sequencing. Expression levels in the tumours and non-cancerous tis...

Parsafar(Soha),Hematti(Simin),Ghorbani(Fat... Cancer Biomark 2016-06-27

...PIK3CA.,To date, there has been no report on the association between polymorphism of PIK3CA gene microsatellites and ris...

Suga(Yasuko),Sugai(Tamotsu),Uesugi(Noriyuk... Pathol Int 2016-01-12

...PIK3CA), DNA methylation and microsatellite instability (MSI) status. In addition, loss of PTEN protein expression was e...

Napolitano(Stefania),Martini(Giulia),Rinal... Clin Cancer Res 2016-04-19

...PIK3CA-AKT pathways has been implicated in the resistance to anti-EGFR mAbs. We have investigated the role of regorafeni...

Sholl(Lynette M),Aisner(Dara L),Varella-Ga... J Thorac Oncol 2016-03-21

...PIK3CA) using SNaPshot, mass spectrometry, Sanger sequencing+/- peptide nucleic acid and/or sizing assays, along with an...

Kim(Shinn Young),Jung(Seung-Hyun),Kim(Min ... Oncotarget 2016-05-02

...PIK3CA and AKT1), copy number alterations (CNAs) and chromothripses, but had significantly fewer driver genes and co-occ...

Corcoran(Ryan B),Atreya(Chloe E),Falchook(... J Clin Oncol 2016-03-08

...PIK3CA mutations. Neither PTEN loss nor microsatellite instability correlated with efficacy. Responses to dabrafenib plu...

Ooft(Marc L),Braunius(Weibel W),Heus(Pauli... Biomark Med 2016-08-09

...PIK3CA, STAT3, STAT5, PTEN, AKT, mTOR, GRB2, SOS, RAF, RAS, MAPK, ERK, MEK and CCND1 in nasopharyngeal carcinoma was ass...

Lochhead(Paul),Nishihara(Reiko),Qian(Zhi R... Am J Clin Nutr 2016-02-08

...PIK3CA mutations, and long interspersed nucleotide element 1 methylation level) were available for a subset of cases. We...

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