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Murata-Kamiya(N),Del Valle Lazarte(AA),Kik... Sci Rep 2026-03-12

...BRCA1, which promotes its nuclear translocation. In the nucleus, BRCA1 protects stalled replication forks and repairs do...

Fang(P),Saunders(A),Minn(K),Chua(KJ),Brook... NPJ Precis Oncol 2026-03-12

...BRCA1/2 and RAD51 paralogs, suggesting a shared HR program. Functionally, transient knockdown of FOXM1 or MYC reduced BR...

Khan(NU),Lei(H),Fu(J),Lei(R),Chen(X),Alqar... J Transl Med 2026-03-12

BACKGROUND: The breast cancer (BC) susceptibility genes 1 (BRCA1) and BC susceptibility genes 2 (BRCA2) are critical gen...

Hawsawi(YM),Mansoor(I),Sayan(M),Alsaleem(M... Int J Surg Pathol 2026-08-00

...BRCA1 and BRCA2. To clarify the clinicopathological impact of somatic PALB2 variants, we analyzed tumor DNA extracted fr...

Yang(H),Zhou(H),Zhao(K),Shi(L),Li(Y),Zhao(... Brain Res Bull 2026-04-00

...BRCA1 expression by directly targeting BRCA1, whereas miR-222 interacted with BRCA1 without affecting its expression. In...

Patel(S),Petrosko(P),Gallo(PH),Myers(M),Gi... Ann Surg Oncol 2026-07-00

...BRCA1 associated RING domain 1 (BARD1) (48%) genes, with zinc finger homeobox 3 (ZFHX3) (29%) and adhesion G protein-cou...

Liu(X),Chen(J),Shen(X),Li(L) Cancer Chemother Pharmacol 2026-03-14

...BRCA1/2 mutations or are BRCA-negative. However, a phase II study of 33 CRC patients receiving mono-olaparib therapy rev...

Tooming(M),Toome(K),Rekker(K),Roht(L),Laid... Sci Rep 2026-03-13

...BRCA1 (6.9% BC; 16.3% OC), BRCA2 (3.8%; 4.5%), and CHEK2 (3.5%; 1.7%). Two BRCA1 PV, c.5266dup and c.4035del, accounted ...

Xiao(JJ),Li(Y),Yang(L),Chen(HM),Hu(JW),Hu(... FASEB J 2026-03-31

...BRCA1-associated protein 1 (BAP1) through the N-terminal residues 1-29. The binding reduces the stability of the LKB1-MO...

Yamazawa(K),Ueki(A),Kuga(A),Hinoi(T),Niits... J Med Genet 2026-05-25

...BRCA1/2 genetic testing serves as a companion diagnostic for poly (ADP-ribose) polymerase inhibitor therapy in Japan, un...