...PIK3CA, and AKT1. Enrichment analysis revealed that these targets are primarily involved in the regulation of the PI3K-A...
...PIK3CA for tumor growth both in vitro and in vivo. We first generated a "KPA" cell line by genetically deleting Pik3ca f...
...PIK3CA, KRAS, APC, and FBXW7. Urine cfDNA also captured several mutations absent from plasma or tissue, supporting its c...
...PIK3CA. Enrichment analysis confirmed their involvement in critical oncogenic pathways. Molecular docking showed strong ...
...PIK3CA and BRAF, provide valuable insights into tumor biology, therapeutic resistance, and response to targeted therapie...
...PIK3CA, FOXA1, and TBX3 mutations were more prevalent in elderly patients. By leveraging the aforementioned mutational c...
...PIK3CA, PTEN, RAD50, BLM, NF1, AR, BRCA2, and KMT2C. Notably, PIK3CA mutations were significantly more frequent in geria...
...PIK3CA mutations with anthracycline-free regimens remains unclear. Methods: We retrospectively analyzed 56 patients with...
...PIK3CA, CASP3, HRAS-and four core targets for icariin treatment-IL6, TNF, STAT3, and INS. Gene ontology (GO) and Kyoto E...
...PIK3CA (≈20%), consistent with established molecular pathways in UBC. Less frequent but potentially actionable alteratio...
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