样本量：12 物种：Homo sapiens 类型：RNA-seq of coding RNA 2019年10月14日

In this study monoclonal cell lines carrying mutations in snoRNA genes (SNORD74, SNORD75, SNORD77, SNORD80) were obtaine...

样本量：9 物种：Homo sapiens 类型：transcription profiling by array 2019年7月23日

CRISPR-Cas9 was used to generate HNF1a mutants (+/- and -/-) in human embryonic stem cell lines and used an in vitro dif...

样本量：7 物种：Homo sapiens 类型：other 2015年1月6日

...CRISPR (KO), unedited controls (WT), or cells transfected with GFP instead of CRISPR. Libraries were generated with a 4n...

样本量：7 物种：Homo sapiens 类型：DNA-seq 2016年8月15日

...CRISPR/Cas9 mediated 1.4kb deletion of the genomic region harboring rs7903146 in the HCT116 cell line followed by global...

样本量：6 物种：Homo sapiens 类型：DNA-seq 2019年7月10日

...CRISPR genetic screens were started 10 days post transduction. >1000-fold coverage of mutagenized cells (libraries A and...

样本量：165 物种：Homo sapiens, Mus musculus 类型：genotyping by high throughput sequencing 2018年9月25日

CRISPR/Cas9-mediated base editing allows to interchange purine bases or pyrimidine bases independent of homology directe...

样本量：6 物种：Homo sapiens 类型：RNA-seq of coding RNA 2017年3月5日

...CRISPR/Cas9 method. Here we studied differential gene expression from wild type and RNH1 knock out K562 cells by RNA-Seq...

样本量：9 物种：Homo sapiens 类型：RNA-seq of coding RNA 2015年8月10日

...CRISPR/Cas9 to introduce the P95H mutation to SRSF2 in K562 leukemia cells, generating an isogenic model so that splicin...

样本量：7 物种：Mus musculus 类型：ChIP-seq, RNA-seq of coding RNA 2014年12月9日

...CRISPR strategy. Allele-specific of Sox2 transcripts in heterozygous enhancer-deletion clones showed that the enhancer a...

样本量：23 物种：Homo sapiens 类型：transcription profiling by array 2015年1月18日

...CRISPR/Cas9 or lentivirus vector system. Each engineered gene and engineered methods are described as a single alphabet ...