样本量：36 物种：Homo sapiens 类型：transcription profiling by array 2014年1月24日

...BRCA1-deficient cells might extensively rewire the HR repair network and confer resistance to PARP inhibitor, partially ...

样本量：13 物种：Homo sapiens 类型：transcription profiling by array 2014年1月1日

...BRCA1, RAD51, and MSH2, which are predicted to be regulated by transcription factor E2F1. Functional assays support thes...

样本量：8 物种：Homo sapiens 类型：transcription profiling by array 2013年12月31日

...BRCA1-depleted cells and increased in BRCA1-overexpressing cells. Our findings raised the question whether BRCA1 affects...

样本量：124 物种：Mus musculus 类型：comparative genomic hybridization by ... 2013年12月1日

...BRCA1 mutation, suggesting that BRCA1 function is required for resistance. Here we show that secondary Brca1 mutations a...

样本量：59 物种：Mus musculus 类型：transcription profiling by array 2013年10月30日

We previously generated genetically engineered mouse (GEM) models based on perturbation of Tp53, Rb with or without Brc...

样本量：9 物种：Mus musculus 类型：transcription profiling by array 2013年10月19日

...BRCA1 occupancy on L1 LINEs, resulting in closed chromatin without ubiquitination of histone H2A. This mechanism appeare...

样本量：67 物种：Homo sapiens 类型：transcription profiling by array 2013年10月14日

...BRCA1 and BRCA2.

样本量：11 物种：Homo sapiens 类型：ChIP-seq, RNA-seq of coding RNA 2013年9月30日

...BRCA1 and PALB2) and phosphorylated RNAPII (P-Ser2) in MCF10A cells by ChIP-seq. Effect of BRCA1 and PALB2 knockdown (sh...

样本量：18 物种：Homo sapiens 类型：transcription profiling by array 2013年9月30日

Breast and ovarian cancer susceptibility genes, BRCA1 and PALB2 have enigmatic roles in cellular growth and mammalian de...

样本量：24 物种：Homo sapiens 类型：transcription profiling by array 2013年9月30日

Breast and ovarian cancer susceptibility genes, BRCA1 and PALB2 have enigmatic roles in cellular growth and mammalian de...