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Insulator dysfunction and oncogene activation in IDH mutant gliomas

样本量:33 物种:Homo sapiens 类型:ChIP-seq 2015年12月23日

...CRISPR-mediated disruption of the CTCF binding sequence in IDH wildtype gliomaspheres induces PDGFRA expression and incr...

Differential contribution of cis-regulatory elements to higher order chromati...

样本量:5 物种:Homo sapiens 类型:ChIP-seq 2016年1月7日

...CRISPR/Cas9 editing of cis-regulatory elements and siRNA-mediated depletion of architectural proteins to determine the r...

Transcription profiling by array of human embryonic stem cells treated with t...

样本量:12 物种:Homo sapiens 类型:transcription profiling by array 2015年9月20日

...CRISPR/Cas9-mediated deletion, shRNA or neutralizing antibodies causes reduced hESC growth, cell death and loss of pluri...

The landscape of accessible chromatin in mammalian pre-implantation embryos

样本量:51 物种:Mus musculus 类型:ChIP-seq, RNA-seq of coding RNA 2016年6月15日

...CRISPR/Cas9-assisted mitochondrial DNA depletion. We show that despite extensive parental asymmetry in DNA methylomes, t...

Low dose irradiation enhances gene targeting in human pluripotent stem cells

样本量:4 物种:Homo sapiens 类型:transcription profiling by array 2016年3月22日

...CRISPRs). Whole exome sequencing confirmed that the LDI to hPSCs did not induce gross genomic alterations, or affect ce...

RNA-seq of CN, CN/AML, and CN/AML BAALC KO iPSCs-derived HSPCs

样本量:15 物种:Homo sapiens, Homo sapiens 类型:RNA-seq of coding RNA, Cell line - Hi... 2021年3月8日

...CRISPR/Cas9 gene-editing. Consequently, we performed in vitro embryoid body (EB)-based hematopoietic and myeloid differe...

ChIP-seq for histone modifications and chromatin factors in H3.3 mutant (K9A;...

样本量:74 物种:Mus musculus, Mus musculus 类型:ChIP-seq 2024年3月9日

...CRISPR-Cas9 to mutate the H3f3b locus, in order to carry homozygous lysine-to-alanine substitution of residues K9, K27 o...

Comparative single cell RNA seq of gastruloids from mESCs grown in 3 distinct...

样本量:25 物种:Mus musculus, Mus musculus 类型:RNA-seq of coding RNA 2024年11月13日

...CRISPR-Cas9 mediated heterozygous knock-in of a Bra/T reporter allele (p2a-H2B-eGFP) as well as a ubiquitous nuclear mar...

Amplicon Sequencing of gRNAs from Brunello CRISPR mutagenized U87MG or eHAP c...

样本量:4 物种:Homo sapiens, Homo sapiens 类型:DNA-seq 2022年9月10日

eHAP or U87MG cells were stably transduced with lentiCas9-Blast (Addgene, #52962) and subsequently selected using Blast...

The tomato MYB21 acts in ovules to mediate jasmonate-regulated fertility (Mic...

样本量:18 物种:Solanum lycopersicum 类型:transcription profiling by array 2019年10月15日

...CRISPR/Cas9 mutants were created and a TILLING mutant was identified, all showing female sterility and therefore corrobo...

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