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Transcription profiling by array of human embryonic stem cells treated with t...

样本量:12 物种:Homo sapiens 类型:transcription profiling by array 2015年9月20日

...CRISPR/Cas9-mediated deletion, shRNA or neutralizing antibodies causes reduced hESC growth, cell death and loss of pluri...

The landscape of accessible chromatin in mammalian pre-implantation embryos

样本量:51 物种:Mus musculus 类型:ChIP-seq, RNA-seq of coding RNA 2016年6月15日

...CRISPR/Cas9-assisted mitochondrial DNA depletion. We show that despite extensive parental asymmetry in DNA methylomes, t...

Low dose irradiation enhances gene targeting in human pluripotent stem cells

样本量:4 物种:Homo sapiens 类型:transcription profiling by array 2016年3月22日

...CRISPRs). Whole exome sequencing confirmed that the LDI to hPSCs did not induce gross genomic alterations, or affect ce...

RNA-seq of CN, CN/AML, and CN/AML BAALC KO iPSCs-derived HSPCs

样本量:15 物种:Homo sapiens, Homo sapiens 类型:RNA-seq of coding RNA, Cell line - Hi... 2021年3月8日

...CRISPR/Cas9 gene-editing. Consequently, we performed in vitro embryoid body (EB)-based hematopoietic and myeloid differe...

ChIP-seq for histone modifications and chromatin factors in H3.3 mutant (K9A;...

样本量:74 物种:Mus musculus, Mus musculus 类型:ChIP-seq 2024年3月9日

...CRISPR-Cas9 to mutate the H3f3b locus, in order to carry homozygous lysine-to-alanine substitution of residues K9, K27 o...

Comparative single cell RNA seq of gastruloids from mESCs grown in 3 distinct...

样本量:25 物种:Mus musculus, Mus musculus 类型:RNA-seq of coding RNA 2024年11月13日

...CRISPR-Cas9 mediated heterozygous knock-in of a Bra/T reporter allele (p2a-H2B-eGFP) as well as a ubiquitous nuclear mar...

Amplicon Sequencing of gRNAs from Brunello CRISPR mutagenized U87MG or eHAP c...

样本量:4 物种:Homo sapiens, Homo sapiens 类型:DNA-seq 2022年9月10日

eHAP or U87MG cells were stably transduced with lentiCas9-Blast (Addgene, #52962) and subsequently selected using Blast...

The tomato MYB21 acts in ovules to mediate jasmonate-regulated fertility (Mic...

样本量:18 物种:Solanum lycopersicum 类型:transcription profiling by array 2019年10月15日

...CRISPR/Cas9 mutants were created and a TILLING mutant was identified, all showing female sterility and therefore corrobo...

Site- and allele-specific de-silencing of polycomb repressive activity by ins...

样本量:6 物种:Homo sapiens 类型:ChIP-seq 2014年7月10日

...CrispR assays, we demonstrate that such insertions induce selective switch from H3K27me3 to H3K27ac at the inserted but ...

Effects on the transcriptome upon deletion of distal elements are not correla...

样本量:32 物种:Homo sapiens 类型:ChIP-seq, other, RNA-seq of coding RN... 2016年1月12日

...CRISPR/Cas9 nuclease to delete 2 CRC risk-associated H3K27Ac peaks (E7 and E24), a peak that is not associated with CRC ...

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