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Site- and allele-specific de-silencing of polycomb repressive activity by ins...

样本量:6 物种:Homo sapiens 类型:ChIP-seq 2014年7月10日

...CrispR assays, we demonstrate that such insertions induce selective switch from H3K27me3 to H3K27ac at the inserted but ...

An autoregulatory enhancer controls mammary-specific STAT5 functions

样本量:10 物种:Mus musculus 类型:ChIP-seq, RNA-seq of coding RNA 2015年9月5日

...CRISPR/Cas9-mediated genome editing was used to delete these STAT5 binding sites in mice and determine their biological ...

Effects on the transcriptome upon deletion of distal elements are not correla...

样本量:32 物种:Homo sapiens 类型:ChIP-seq, other, RNA-seq of coding RN... 2016年1月12日

...CRISPR/Cas9 nuclease to delete 2 CRC risk-associated H3K27Ac peaks (E7 and E24), a peak that is not associated with CRC ...

Functions of BET proteins in GATA1-mediated transcription [ChIP-seq]

样本量:15 物种:Mus musculus 类型:ChIP-seq 2015年2月23日

...CRISPR/CAS9-mediated genomic engineering and shRNA approaches we observed that depletion of either BRD2 or BRD4 alone bl...

The landscape of accessible chromatin in mammalian pre-implantation embryos (...

样本量:32 物种:Mus musculus 类型:RNA-seq of coding RNA 2016年6月15日

...CRISPR/Cas9-assisted mitochondrial DNA depletion. We show that despite extensive parental asymmetry in DNA methylomes, t...

The landscape of accessible chromatin in mammalian pre-implantation embryos (...

样本量:17 物种:Mus musculus 类型:ChIP-seq 2016年6月15日

...CRISPR/Cas9-assisted mitochondrial DNA depletion. We show that despite extensive parental asymmetry in DNA methylomes, t...

The landscape of accessible chromatin in mammalian pre-implantation embryos (...

样本量:2 物种:Mus musculus 类型:ChIP-seq 2016年6月15日

...CRISPR/Cas9-assisted mitochondrial DNA depletion. We show that despite extensive parental asymmetry in DNA methylomes, t...

The tomato MYB21 acts in ovules to mediate jasmonate-regulated fertility (Mic...

样本量:18 物种:Solanum lycopersicum 类型:transcription profiling by array 2019年10月15日

...CRISPR/Cas9 mutants were created and a TILLING mutant was identified, all showing female sterility and therefore corrobo...

Engineering of a promoterless anti-viral RNAi hairpin into an endogenous miRN...

样本量:12 物种:Homo sapiens 类型:transcription profiling by array 2015年5月7日

...CRISPR to integrate an anti-hepatitis C virus (HCV) shmiRNA into the liver-specific miR-122/hcr gene. Reporter assays an...

Engineering of a promoterless anti-viral RNAi hairpin into an endogenous miRN...

样本量:12 物种:Homo sapiens 类型:transcription profiling by array 2015年5月7日

...CRISPR to integrate an anti-hepatitis C virus (HCV) shmiRNA into the liver-specific miR-122/hcr gene. Reporter assays an...

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