样本量：9 物种：Homo sapiens 类型：transcription profiling by array 2019年7月23日

CRISPR-Cas9 was used to generate HNF1a mutants (+/- and -/-) in human embryonic stem cell lines and used an in vitro dif...

样本量：6 物种：Homo sapiens 类型：DNA-seq 2019年7月10日

...CRISPR genetic screens were started 10 days post transduction. >1000-fold coverage of mutagenized cells (libraries A and...

样本量：12 物种：Mus musculus 类型：RNA-seq of coding RNA 2019年7月9日

...CRISPR activation. Cells were first stably transfected with the lenti-MS2-p65-HSF1 activator plasmid. Respective sgRNAs ...

样本量：58 物种：Salmo salar 类型：RNA-seq of coding RNA 2019年4月30日

...CRISPR-mediated elovl2 knockout, we have shown that elovl2 is crucial for multi-tissue synthesis of 22:6n-3 in vivo and ...

样本量：16 物种：Homo sapiens 类型：ChIP-seq 2019年3月28日

...CRISPR-Cas9 approach. 3 clones were generated by single cell cloning and CSF-1R localization on chromatin was compared t...

样本量：12 物种：Homo sapiens 类型：RNA-seq of coding RNA 2019年2月25日

...CRISPR/Cas9 to integrate an A>G mutation in the SF3B1 consensus coding sequence to change the 700th codon from lysine to...

样本量：9 物种：Homo sapiens 类型：transcription profiling by array 2019年1月24日

Persistent activation of canonical and non-canonical NF-κB pathways is a hallmark of the malignant Hodgkin and Reed-Ster...

样本量：8 物种：Homo sapiens 类型：RNA-seq of coding RNA 2018年12月17日

...CRISPR/Cas9 has been used to delete CD5L and RORA in THP-1 human monocytic cell line. Cells transduced with sgRNAs targe...

样本量：30 物种：Homo sapiens 类型：DNA-seq 2018年12月13日

...CRISPR/Cas9 activity and the induced indel profiles. We used two different doses of Trichostatin and two different doses...

样本量：10 物种：Homo sapiens 类型：DNA-seq 2018年12月13日

...CRISPR/Cas9. We used pools of sgRNAs and performed targeted capture and sequencing of the edited regions in HepG2 cells.