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Clonal evolution, genomic drivers, and effects of therapy in chronic lymphocy...

样本量:496 物种:Homo sapiens 类型:comparative genomic hybridization by ... 2013年4月19日

...TP53 mutations results in the outgrowth of genomically very complex clones which dominate at relapse. Using complementar...

Portrait of early-onset breast cancer in Brazilian patients: germline mutatio...

样本量:49 物种:Homo sapiens 类型:transcription profiling by array 2013年4月9日

...TP53 genes, and the respective tumors were investigated regarding hormonal receptors status, HER2 expression. Transcript...

Identifying chromatin associations with promyelocytic leukemia nuclear bodies...

样本量:20 物种:Homo sapiens 类型:ChIP-chip by tiling array 2013年3月28日

...TP53-PML NB association, but were able also to identify novel locus associations such as PML, ABCA7, and TFF1. In addit...

Inactivation of TP53 correlates with disease progression and low miR-34a expr...

样本量:275 物种:Homo sapiens 类型:transcription profiling by array 2013年3月21日

...TP53 mutation status and del17p status. CD19 B-cells from previously treated and relapsed chronic lymphocytic leukemia p...

Minor clone provides a reservoir for relapse in multiple myeloma

样本量:99 物种:Homo sapiens 类型:transcription profiling by array, gen... 2013年2月13日

...TP53 deletions, that seem to reflect progression. By using genome-wide high resolution SNP arrays we identified subclone...

Exome and whole genome sequencing of esophageal adenocarcinoma identifies rec...

样本量:14 物种:Homo sapiens 类型:transcription profiling by array 2013年2月11日

...TP53, CDKN2A, SMAD4, and PIK3CA) have been previously implicated in EAC. The novel significantly mutated genes include s...

Molecular profiling of cutaneous squamous cell carcinomas and actinic keratos...

样本量:94 物种:Homo sapiens 类型:transcription profiling by array 2013年2月6日

...TP53) and genetic alterations (e.g. loss of CDKN2A, amplification of RAS) have been found in SCCs. The aim of this genom...

Genome-wide SNP analysis of cutaneous squamous cell carcinomas and actinic ke...

样本量:94 物种:Homo sapiens 类型:comparative genomic hybridization by ... 2013年2月6日

...TP53) and genetic alterations (e.g. CDKN2A loss, RAS amplification) have been found in SCCs. The aim of this study was t...

The Genetic Basis of Hypodiploid Acute Lymphoblastic Leukemia

样本量:118 物种:Homo sapiens 类型:transcription profiling by array 2013年1月15日

...TP53 alterations (88%), almost half of which are present in non-tumor cells, and have alterations of IKZF2 (HELIOS; 53%)...

ChIP analysis on a custom tiling array of U251 human glioblastoma cell line

样本量:52 物种:Homo sapiens 类型:ChIP-chip by tiling array 2012年12月10日

...tp53 is advantageous for tumor cells, however the molecular mechanism of mutp53 action is still not known. We used the g...

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