...BRCA1/2 mutation carriers have an up to 30 40 fold increased risk to develop ovarian cancer, preferentially HGSEMC. De...
...BRCA1 expression and NtAI in sporadic TNBC and serous ovarian cancers without BRCA1 or BRCA2 mutation. Thus, accumulatio...
We previously generated genetically engineered mouse (GEM) models based on perturbation of Tp53, Rb with or without Brc...
...BRCA1 and NF1 genes that caused exon exclusion suggest a role for DAZAP1 in RNA splicing. To elucidate the biological fu...
...BRCA1, RAD51, and MSH2, which are predicted to be regulated by transcription factor E2F1. Functional assays support thes...
...BRCA1/2 and Redox pathways, DNA repair (HR, NHEJ and MMR), FA family and IgLON family. 111 ovarian tumor samples were as...
...Brca1/2 following injection of adenovirus expressing Cre recombinase into the ovarian bursa. These models develop metast...
...BRCA1, BRCA2 and TP53 genes and large genomic rearrangements mapped on chromosome 7q. Genomic rearrangements were assess...
...BRCA1-BCLAF1-SF3B1 protein complex showed differential expression/splicing in SF3B1 mutant cases. Our data indicate that...
...BRCA1 mutation carriers, 10 BRCA2 mutation carriers and 43 non-BRCA12 tumors denominated hereafter as BRCAX tumors. In a...
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