...BRCA1 gene mutation: 27 patients had germline BRCA1 gene mutation, one had somatic mutation, 70 had no BRCA1 mutation de...
...BRCA1/2 breast cancer families in order to identify additional high-risk breast cancer susceptibility genes. We applied ...
...BRCA1 or BRCA2 mutations in individual patients, loss of BRCA1 promoter methylation, an alteration in molecular subtype,...
...BRCA1 tumor suppressor locus. Using siRNAs in breast cancer cell lines, we showed that the 17q21.3 amplicon harbored a s...
...BRCA1, BRCA2 or ATM mutation, or from non-BRCA1/2 families. We found that replicate samples correlated well with each ot...
...BRCA1/2 germinal mutations and Mismatch Repair (MMR) defects, using next generation sequencing approach on DNA from form...
...BRCA1 expression is reduced in oocytes obtained from old females and RNAi-mediated reduction of BRCA1 in oocytes obtaine...
...BRCA1-associated breast cancers.
...BRCA1 in DNA Damage Response’ was predicted to be the most significantly altered canonical pathway involved in intrinsic...
...BRCA1 A375 cells were grown, transfected with siRNA, incubated for 48hrs, then incubated for another 26hrs in the presen...
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