...TP53 Knockout, and Multiple Colorectal Cancer Cell Lines Undergoing Treatment or Remaining Untreated with Various Inhibi...
...TP53 or MLH1 knockout (KO) were subjected to a genome-wide CRISPR-Cas9 knockout screen to identify synthetic lethal inte...
...TP53 knockout screen along with additional 93 genes serving as positive and negative controls.
...TP53 and BRCA2 in BC cell lines, which, therefore, share relevant characteristics with primary BC. Furthermore, we showe...
...TP53 alleles, leaving only one functional copy of TP53. The remaining TP53 allele was altered by inserting a LoxP-flanke...
...TP53 mutant variants in exon-wide mutant cell libraries, comprehensive mutome libraries of TP53 affecting the Exons 5, 6...
...TP53 mutant variants in exon-wide mutant cell libraries, comprehensive mutome libraries of TP53 affecting the Exons 5, 6...
...TP53 mutations. To this end, cells were haploidized by deleting an intronic splice site in one of the two wild-type TP53...
...TP53-dependency upon oxidative and oncogenic stress induction. Since about 50% of human breast cancers have mutant p53 a...
...TP53-dependency upon oxidative and oncogenic stress induction. To investigate the functional roles of KDM7A-DT, we first...
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