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PMID: 964105 Published · ppublish English Journal Article

Analysis of the frequency of sister chromatid exchange in different regions of chromosomes of the kangaroo rat (Dipodomys ordii).

Chromosoma ·Vol. 56 ·No. 3 ·1976-07-08 ·Pages 275-87

Bostock CJ, Christie S

Abstract

The frequency of sister chromatid exchanges (SCEs) has been determined for C band and non-C band regions of chromosomes of the kangaroo rat after staining with the fluorescence plus giemsa (FPG) technique. After one complete round of DNA synthesis in the presence of bromodeoxyuridine (BrdU) staining of the C band regions revealed simple or complex asymmetries between chromatids. After two complete rounds of DNA synthesis in the presence of BrdU "harlequin" chromosomes were observed. Analysis of the distribution of SCE in chromosomes at their 1st and 2nd mitosis showed that relatively few exchanges occur within C band regions, although the frequency of SCEs is high at the junction between C band and non-C band chromosome regions.

MeSH Terms
Animals Bromodeoxyuridine Chromatids Chromosomes/analysis Crossing Over, Genetic DNA, Satellite/analysis Dipodomys Heterochromatin/analysis Rodentia
Chemicals
DNA, Satellite Heterochromatin Bromodeoxyuridine
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Bostock C J
Christie S
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24 references, click to expand
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Article Info
Journal
Chromosoma
Abbr.
Chromosoma
ISSN
0009-5915
DOI
10.1007/BF00293191
Published
1976-07-08
Pages
275-87
Language
English
Region
Austria
NLM ID
2985138R
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00293191 View journal details
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