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PMID: 9327581 Published · ppublish English Comparative Study Journal Article

Factors controlling acid tolerance of Listeria monocytogenes: effects of nisin and other ionophores.

Applied and environmental microbiology ·Vol. 63 ·No. 10 ·1997-10-00 ·Pages 4123-6

Datta AR, Benjamin MM

Abstract

The acid tolerance of a Listeria monocytogenes serotype 4b strain was studied by measuring its ability to survive at an acidic pH at 37 degrees C. The acid tolerance of L. monocytogenes was much lower than those of Escherichia coli O157:H7 and Shigella flexneri strains. This observation suggested a higher infective dose for L. monocytogenes than E. coli O157:H7 and Shigella. The susceptibility of L. monocytogenes to acidic pH was dependent upon growth medium pH and growth phase of the culture. Nisin and some other ionophores reduced the acid tolerance of both stationary-phase and log-phase cultures of L. monocytogenes. These studies indicated that nisin might be a useful candidate for controlling acid tolerance of L. monocytogenes.

MeSH Terms
Animals Culture Media/chemistry Escherichia coli O157/drug effects,metabolism Food Microbiology Humans Hydrogen-Ion Concentration Ionophores/pharmacology Listeria monocytogenes/drug effects,growth & development,metabolism Nisin/pharmacology Shigella flexneri/drug effects,metabolism
Chemicals
Culture Media Ionophores Nisin
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Datta A R
Center for Food Safety and Applied Nutrition, Food and Drug Administration, Washington, D.C. 20204, USA. ARD@VAX8.CFSAN.FDA.GOV
Benjamin M M
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Article Info
Journal
Applied and environmental microbiology
Abbr.
Appl Environ Microbiol
ISSN
0099-2240
DOI
10.1128/aem.63.10.4123-4126.1997
Email
ard@vax8.cfsan.fda.gov
Published
1997-10-00
Pages
4123-6
Language
English
Region
United States
NLM ID
7605801
PMCID
PMC168728
Subset
IM
External Links
PubMed source DOI: 10.1128/aem.63.10.4123-4126.1997 PMC Full Text View journal details
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