Home LiteratureArticle Details
PMID: 9281574 Published · ppublish English Journal Article Review

Pathways of spindle pole formation: different mechanisms; conserved components.

The Journal of cell biology ·Vol. 138 ·No. 5 ·1997-09-08 ·Pages 953-6

Merdes A, Cleveland DW

Abstract

暂无摘要

MeSH Terms
Animals Centrosome/physiology Dynactin Complex Dyneins/metabolism Microtubule-Associated Proteins/metabolism Microtubules/physiology Nuclear Proteins/metabolism Spindle Apparatus/physiology
Chemicals
Dynactin Complex Microtubule-Associated Proteins Nuclear Proteins Dyneins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Merdes A
Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, California 92093-0660, USA.
Cleveland D W
References (32)
32 references, click to expand
  1. Centrosomes and mitotic poles.
    Exp Cell Res. 1984 Jul;153(1):1-15 PMID: 6734733
  2. Mitotic spindle poles are organized by structural and motor proteins in addition to centrosomes.
    J Cell Biol. 1997 Sep 8;138(5):1055-66 PMID: 9281583
  3. Beyond self-assembly: from microtubules to morphogenesis.
    Cell. 1986 May 9;45(3):329-42 PMID: 3516413
  4. Sites of microtubule assembly and disassembly in the mitotic spindle.
    Cell. 1986 May 23;45(4):515-27 PMID: 3708686
  5. Microtubule dynamics investigated by microinjection of Paramecium axonemal tubulin: lack of nucleation but proximal assembly of microtubules at the kinetochore during prometaphase.
    J Cell Biol. 1989 Mar;108(3):939-53 PMID: 2646309
  6. The motor for poleward chromosome movement in anaphase is in or near the kinetochore.
    J Cell Biol. 1989 Nov;109(5):2245-55 PMID: 2808528
  7. Mechanically cut mitotic spindles: clean cuts and stable microtubules.
    J Cell Sci. 1989 Nov;94 ( Pt 3):415-23 PMID: 2698889
  8. Cytoplasmic dynein is localized to kinetochores during mitosis.
    Nature. 1990 May 17;345(6272):263-5 PMID: 2139717
  9. Localization of cytoplasmic dynein to mitotic spindles and kinetochores.
    Nature. 1990 May 17;345(6272):266-8 PMID: 2139718
  10. Taxol-induced microtubule asters in mitotic extracts of Xenopus eggs: requirement for phosphorylated factors and cytoplasmic dynein.
    J Cell Biol. 1991 Mar;112(6):1177-87 PMID: 1671864
  11. Ability to organize microtubules in taxol-treated mitotic PtK2 cells goes with the SPN antigen and not with the centrosome.
    J Cell Sci. 1992 May;102 ( Pt 1):91-102 PMID: 1354220
  12. Mitotic spindle organization by a plus-end-directed microtubule motor.
    Nature. 1992 Oct 8;359(6395):540-3 PMID: 1406972
  13. gamma-Tubulin is present in acentriolar MTOCs during early mouse development.
    J Cell Sci. 1993 May;105 ( Pt 1):157-66 PMID: 8360270
  14. Interpolar spindle microtubules in PTK cells.
    J Cell Biol. 1993 Dec;123(6 Pt 1):1475-89 PMID: 8253845
  15. Chromokinesin: a DNA-binding, kinesin-like nuclear protein.
    J Cell Biol. 1995 Mar;128(5):761-8 PMID: 7876303
  16. Xklp1, a chromosomal Xenopus kinesin-like protein essential for spindle organization and chromosome positioning.
    Cell. 1995 Apr 7;81(1):117-27 PMID: 7720067
  17. DNA binding and meiotic chromosomal localization of the Drosophila nod kinesin-like protein.
    Cell. 1995 Apr 7;81(1):129-38 PMID: 7720068
  18. NuMA is required for the organization of microtubules into aster-like mitotic arrays.
    J Cell Biol. 1995 Nov;131(3):693-708 PMID: 7593190
  19. Affinity chromatography demonstrates a direct binding between cytoplasmic dynein and the dynactin complex.
    J Biol Chem. 1995 Dec 1;270(48):28806-11 PMID: 7499404
  20. Nucleation of microtubule assembly by a gamma-tubulin-containing ring complex.
    Nature. 1995 Dec 7;378(6557):578-83 PMID: 8524390
  21. Cytoplasmic dynein binds dynactin through a direct interaction between the intermediate chains and p150Glued.
    J Cell Biol. 1995 Dec;131(6 Pt 1):1507-16 PMID: 8522607
  22. A bipolar kinesin.
    Nature. 1996 Jan 18;379(6562):270-2 PMID: 8538794
  23. Xklp2, a novel Xenopus centrosomal kinesin-like protein required for centrosome separation during mitosis.
    Cell. 1996 Jan 12;84(1):49-59 PMID: 8548825
  24. Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis.
    J Cell Biol. 1996 Feb;132(4):617-33 PMID: 8647893
  25. Anastral meiotic spindle morphogenesis: role of the non-claret disjunctional kinesin-like protein.
    J Cell Biol. 1996 Jul;134(2):455-64 PMID: 8707829
  26. Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts.
    Nature. 1996 Aug 1;382(6590):420-5 PMID: 8684481
  27. Opposing motor activities are required for the organization of the mammalian mitotic spindle pole.
    J Cell Biol. 1996 Oct;135(2):399-414 PMID: 8896597
  28. A complex of NuMA and cytoplasmic dynein is essential for mitotic spindle assembly.
    Cell. 1996 Nov 1;87(3):447-58 PMID: 8898198
  29. NuMA assembles into an extensive filamentous structure when expressed in the cell cytoplasm.
    J Cell Sci. 1996 Mar;109 ( Pt 3):619-30 PMID: 8907707
  30. Monastral bipolar spindles: implications for dynamic centrosome organization.
    J Cell Sci. 1997 Feb;110 ( Pt 4):451-64 PMID: 9067597
  31. Spindle assembly in Xenopus egg extracts: respective roles of centrosomes and microtubule self-organization.
    J Cell Biol. 1997 Aug 11;138(3):615-28 PMID: 9245790
  32. Microtubule assembly nucleated by isolated centrosomes.
    Nature. 1984 Nov 15-21;312(5991):232-7 PMID: 6504137
Article Info
Journal
The Journal of cell biology
Abbr.
J Cell Biol
ISSN
0021-9525
DOI
10.1083/jcb.138.5.953
Published
1997-09-08
Pages
953-6
Language
English
Region
United States
NLM ID
0375356
PMCID
PMC2136757
Subset
IM
External Links
PubMed source DOI: 10.1083/jcb.138.5.953 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2