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The Fas death factor.
Science. 1995 Mar 10;267(5203):1449-56
PMID: 7533326
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Identification of soluble APO-1 in supernatants of human B- and T-cell lines and increased serum levels in B- and T-cell leukemias.
Blood. 1995 Mar 15;85(6):1562-9
PMID: 7534137
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Expression of the bcl-2 gene family in normal and malignant breast tissue: low bax-alpha expression in tumor cells correlates with resistance towards apoptosis.
Int J Cancer. 1995 Mar 16;60(6):854-9
PMID: 7896458
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Involvement of apoptosis antigen Fas in clonal deletion of human thymocytes.
Int Immunol. 1994 Dec;6(12):1849-56
PMID: 7535095
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Expression of the Fas ligand in cells of T cell lineage.
J Immunol. 1995 Apr 15;154(8):3806-13
PMID: 7706720
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FAP-1: a protein tyrosine phosphatase that associates with Fas.
Science. 1995 Apr 21;268(5209):411-5
PMID: 7536343
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Lymphocyte apoptosis induced by CD95 (APO-1/Fas) ligand-expressing tumor cells--a mechanism of immune evasion?
Nat Med. 1996 Dec;2(12):1361-6
PMID: 8946836
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Interferon-gamma induces Ice gene expression and enhances cellular susceptibility to apoptosis in the U937 leukemia cell line.
Biochem Biophys Res Commun. 1996 Dec 4;229(1):21-6
PMID: 8954078
-
Cotransplantation of allogeneic islets with allogeneic testicular cell aggregates allows long-term graft survival without systemic immunosuppression.
Diabetes. 1997 Feb;46(2):317-22
PMID: 9000711
-
CD95 ligand (FasL)-induced apoptosis is necessary for corneal allograft survival.
J Clin Invest. 1997 Feb 1;99(3):396-402
PMID: 9022072
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Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53.
J Clin Invest. 1997 Feb 1;99(3):403-13
PMID: 9022073
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The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand.
J Exp Med. 1996 Sep 1;184(3):1075-82
PMID: 9064324
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Lethal effect of the anti-Fas antibody in mice.
Nature. 1993 Aug 26;364(6440):806-9
PMID: 7689176
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Fas antigen is the major target molecule for CD4+ T cell-mediated cytotoxicity.
J Immunol. 1994 Feb 1;152(3):1127-33
PMID: 7507960
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Anti-Fas on nonhematopoietic tumors: levels of Fas/APO-1 and bcl-2 are not predictive of biological responsiveness.
Cancer Res. 1994 Mar 15;54(6):1580-6
PMID: 7511047
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Expression of APO-1 (CD95), a member of the NGF/TNF receptor superfamily, in normal and neoplastic colon epithelium.
Int J Cancer. 1994 May 1;57(3):371-7
PMID: 8168998
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Expression of functional Fas antigen on adult T-cell leukemia.
Leuk Res. 1994 Apr;18(4):305-10
PMID: 7513372
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A tumor-suppressor function for Fas (CD95) revealed in T cell-deficient mice.
J Exp Med. 1996 Sep 1;184(3):1149-54
PMID: 9064331
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The CTL's kiss of death.
Cell. 1995 Apr 7;81(1):9-12
PMID: 7536631
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Myeloma cells express Fas antigen/APO-1 (CD95) but only some are sensitive to anti-Fas antibody resulting in apoptosis.
Blood. 1995 Feb 1;85(3):757-64
PMID: 7530506
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Defective expression of hematopoietic cell protein tyrosine phosphatase (HCP) in lymphoid cells blocks Fas-mediated apoptosis.
Immunity. 1995 Apr;2(4):353-62
PMID: 7536621
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Lymphokine-activated killer (LAK) cells. Analysis of factors relevant to the immunotherapy of human cancer.
Cancer. 1985 Mar 15;55(6):1327-33
PMID: 3871657
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Monoclonal antibody-mediated tumor regression by induction of apoptosis.
Science. 1989 Jul 21;245(4915):301-5
PMID: 2787530
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Effect of bcl-2 on Fas antigen-mediated cell death.
J Immunol. 1993 Jul 15;151(2):621-7
PMID: 7687619
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Participation of target Fas protein in apoptosis pathway induced by CD4+ Th1 and CD8+ cytotoxic T cells.
Proc Natl Acad Sci U S A. 1994 May 10;91(10):4185-9
PMID: 7514297
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Activation induces sensitivity toward APO-1 (CD95)-mediated apoptosis in human B cells.
J Immunol. 1994 Jun 15;152(12):5624-32
PMID: 7515909
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Apoptotic cell death induced by a mouse-human anti-APO-1 chimeric antibody leads to tumor regression.
Int J Cancer. 1994 Aug 15;58(4):562-7
PMID: 7520027
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Anti-Fas/APO-1 antibody-mediated apoptosis of cultured human glioma cells. Induction and modulation of sensitivity by cytokines.
J Clin Invest. 1994 Sep;94(3):954-64
PMID: 7521890
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APO-1 (CD95) mediated apoptosis in human T-ALL engrafted in SCID mice.
Leukemia. 1994 Nov;8(11):1825-33
PMID: 7526086
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Fas ligand mediates activation-induced cell death in human T lymphocytes.
J Exp Med. 1995 Jan 1;181(1):71-7
PMID: 7528780
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Granzyme A is an interleukin 1 beta-converting enzyme.
J Exp Med. 1995 May 1;181(5):1917-22
PMID: 7722467
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Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis.
Nature. 1995 May 4;375(6526):81-3
PMID: 7536901
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Granzyme B is inhibited by the cowpox virus serpin cytokine response modifier A.
J Biol Chem. 1995 May 5;270(18):10377-9
PMID: 7737968
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FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis.
Cell. 1995 May 19;81(4):505-12
PMID: 7538907
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RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death.
Cell. 1995 May 19;81(4):513-23
PMID: 7538908
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Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression.
Mol Cell Biol. 1995 Jun;15(6):3032-40
PMID: 7539102
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Protooncogene bcl-2 gene transfer abrogates Fas/APO-1 antibody-mediated apoptosis of human malignant glioma cells and confers resistance to chemotherapeutic drugs and therapeutic irradiation.
J Clin Invest. 1995 Jun;95(6):2633-43
PMID: 7539458
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Expression and function of Fas (APO-1/CD95) in patient myeloma cells and myeloma cell lines.
Blood. 1995 Jun 15;85(12):3566-76
PMID: 7540067
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Dysregulated Fas and Bcl-2 expression leading to enhanced apoptosis in T cells of multiple myeloma patients.
Blood. 1995 Jun 15;85(12):3679-87
PMID: 7540069
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Bcl-x and Bcl-2 inhibit TNF and Fas-induced apoptosis and activation of phospholipase A2 in breast carcinoma cells.
Oncogene. 1995 Jun 15;10(12):2297-305
PMID: 7540278
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Loss of Fas/Apo-1 receptor accelerates lymphomagenesis in E mu L-MYC transgenic mice but not in animals infected with MoMuLV.
Oncogene. 1995 Jun 15;10(12):2397-401
PMID: 7784089
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Fas/APO-1 gene transfer for human malignant glioma.
Cancer Res. 1995 Jul 1;55(13):2936-44
PMID: 7540953
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Soluble Fas/APO-1 in tumor cells: a potential regulator of apoptosis?
Cancer Lett. 1995 Jul 20;94(1):1-8
PMID: 7542559
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Expression of Fas/Apo-1 (CD95) and apoptosis in tumor cells from patients with plasma cell disorders.
Blood. 1995 Sep 1;86(5):1939-45
PMID: 7544648
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Regulation of the Fas apoptotic cell death pathway by Abl.
J Biol Chem. 1995 Sep 22;270(38):22625-31
PMID: 7545682
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Bcl-XL protects cancer cells from p53-mediated apoptosis.
Oncogene. 1995 Oct 5;11(7):1389-94
PMID: 7478561
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Divergent induction of apoptosis and IL-8 secretion in HT-29 cells in response to TNF-alpha and ligation of Fas antigen.
J Immunol. 1995 Nov 1;155(9):4147-54
PMID: 7594569
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A role for CD95 ligand in preventing graft rejection.
Nature. 1995 Oct 19;377(6550):630-2
PMID: 7566174
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Resistance to Fas-mediated apoptosis in human hepatoma cells.
Oncogene. 1995 Sep 21;11(6):1157-64
PMID: 7566976
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Fas ligand-induced apoptosis as a mechanism of immune privilege.
Science. 1995 Nov 17;270(5239):1189-92
PMID: 7502042
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Induction of Fas-mediated apoptosis in p53-transfected human colon carcinoma cells.
Oncogene. 1995 Nov 16;11(10):1939-46
PMID: 7478511
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Expression of Fas/APO-1 during the progression of astrocytomas.
Cancer Res. 1995 Dec 1;55(23):5528-30
PMID: 7585627
-
A Fas-associated protein factor, FAF1, potentiates Fas-mediated apoptosis.
Proc Natl Acad Sci U S A. 1995 Dec 5;92(25):11894-8
PMID: 8524870
-
Fas involvement in cytotoxicity mediated by human NK cells.
Cell Immunol. 1995 Dec;166(2):236-46
PMID: 7497525
-
Interleukin-1 beta-converting enzyme mediates cisplatin-induced apoptosis in malignant glioma cells.
Cancer Res. 1995 Dec 15;55(24):6166-71
PMID: 8521409
-
Fas/Apo-1 (CD95) receptor lacking the intracytoplasmic signaling domain protects tumor cells from Fas-mediated apoptosis.
J Immunol. 1996 Jan 1;156(1):13-7
PMID: 8598453
-
Regulation of Fas(Apo-1/CD95)- and perforin-mediated lytic pathways of primary cytotoxic T lymphocytes by the protooncogene bcl-2.
Eur J Immunol. 1995 Dec;25(12):3509-13
PMID: 8566045
-
Activated B cells express functional Fas ligand.
Eur J Immunol. 1996 Mar;26(3):721-4
PMID: 8605944
-
Resistance of AIDS-associated Kaposi's sarcoma cells to Fas-mediated apoptosis.
Cancer Res. 1996 Apr 15;56(8):1874-9
PMID: 8620507
-
Fas ligand in human serum.
Nat Med. 1996 Mar;2(3):317-22
PMID: 8612231
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Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis.
Nature. 1996 Apr 25;380(6576):723-6
PMID: 8614469
-
Involvement of the CD95 (APO-1/FAS) receptor/ligand system in drug-induced apoptosis in leukemia cells.
Nat Med. 1996 May;2(5):574-7
PMID: 8616718
-
Signaling through the lymphotoxin beta receptor induces the death of some adenocarcinoma tumor lines.
J Exp Med. 1996 Mar 1;183(3):867-78
PMID: 8642291
-
Overexpression of the death-promoting gene bax-alpha which is downregulated in breast cancer restores sensitivity to different apoptotic stimuli and reduces tumor growth in SCID mice.
J Clin Invest. 1996 Jun 1;97(11):2651-9
PMID: 8647960
-
Prevention of islet allograft rejection with engineered myoblasts expressing FasL in mice.
Science. 1996 Jul 5;273(5271):109-12
PMID: 8658177
-
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex.
Cell. 1996 Jun 14;85(6):817-27
PMID: 8681377
-
Differential expression of Fas (CD95) and Fas ligand on normal human phagocytes: implications for the regulation of apoptosis in neutrophils.
J Exp Med. 1996 Aug 1;184(2):429-40
PMID: 8760796
-
Fas expression and function in normal and malignant breast cell lines.
Cancer Res. 1996 Oct 15;56(20):4791-8
PMID: 8841000
-
Protection against Fas/APO-1- and tumor necrosis factor-mediated cell death by a novel protein, sentrin.
J Immunol. 1996 Nov 15;157(10):4277-81
PMID: 8906799
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Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape.
Science. 1996 Nov 22;274(5291):1363-6
PMID: 8910274
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Decreased tumor surveillance in perforin-deficient mice.
J Exp Med. 1996 Nov 1;184(5):1781-90
PMID: 8920866
-
Systemic injection of a tripeptide inhibits the intracellular activation of CPP32-like proteases in vivo and fully protects mice against Fas-mediated fulminant liver destruction and death.
J Exp Med. 1996 Nov 1;184(5):2067-72
PMID: 8920897