New chromosomal dysmorphic syndromes. 2. Trisomy 10p.

European journal of pediatrics ·Vol. 126 ·No. 3 ·1977-10-12 ·Pages 109-25

Stengel-Rutkowski S, Murken JD, Frankenberger R, Riechert M, Spiess H, Rodewald A, Stene J

Abstract

This is the report of a family in which a balanced translocation in the mother t(5;10)(p15;p13) led to an unbalanced chromosomal constitution in two children. It was identified by G-banding analysis as trisomy of the distal portion of the short arm of chromosome 10 (p13 leads to pter). Comparison with 15 previous reports of trisomy 10p confirms the existence of a characteristic dysmorphic syndrome.

MeSH Terms

Abnormalities, Multiple/etiology Adult Child Chromosomes, Human, 6-12 and X Female Humans Infant Intellectual Disability/etiology Karyotyping Male Pedigree Phenotype Translocation, Genetic Trisomy

Authors & Affiliations

7 authors, click to expand affiliations / ORCID

Stengel-Rutkowski S

Murken J D

Frankenberger R

Riechert M

Spiess H

Rodewald A

Stene J

References (18)

18 references, click to expand

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Article Info

Journal

European journal of pediatrics

Abbr.

Eur J Pediatr

ISSN

0340-6199

DOI

10.1007/BF00442193

Published

1977-10-12

Pages

109-25

Language

English

Region

Germany

NLM ID

7603873

Subset

External Links

PubMed source DOI: 10.1007/BF00442193 View journal details

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New chromosomal dysmorphic syndromes. 2. Trisomy 10p.

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