Partial trisomy 10p.

Humangenetik ·Vol. 29 ·No. 2 ·1975-09-10 ·Pages 141-4

Grosse KP, Schwanitz G, Singer H, Wieczorek V

Abstract

It is reported on a boy of 4 years 9 months with trisomy of the distal part of the short arm of a chromosome 10, due to a balanced 7/10 translocation in the father. Besides multiple minor dysmorphias the patient showed severe mental retardation, small stature, hypotonia, retarded bone age. The high and bulky forehead was especially remarkable, because this sign has also been noted in formerly reported cases with trisomy 10p.

MeSH Terms

Abnormalities, Multiple/genetics Child, Preschool Chromosomes, Human, 6-12 and X Dermatoglyphics Humans Intellectual Disability/genetics Male Pedigree Phenotype Translocation, Genetic Trisomy

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Grosse K P

Schwanitz G

Singer H

Wieczorek V

References (3)

3 references, click to expand

Precise identification of various chromosomal abnormalities.
Ann Hum Genet. 1973 Apr;36(4):375-9 PMID: 4270654
Brother and sister with trisomy 10p: a new syndrome.
Humangenetik. 1974;23(3):163-72 PMID: 4844639
An intersexual infant with an extra chromosome.
Ann Genet. 1968 Jun;11(2):88-94 PMID: 5303428

Article Info

Journal

Humangenetik

Abbr.

Humangenetik

ISSN

0018-7348

DOI

10.1007/BF00430351

Published

1975-09-10

Pages

141-4

Language

English

Region

Germany

NLM ID

7607154

Subset

External Links

PubMed source DOI: 10.1007/BF00430351

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Partial trisomy 10p.

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