Prostaglandin production by human polymorphnuclear leucocytes during phagocytosis in vitro.

Experientia ·Vol. 33 ·No. 7 ·1977-07-15 ·Pages 961-2

Tolone G, Bonasera L, Brai M, Tolone C

Abstract

Human polymorphonuclear leukocytes were found to be able to synthetize and release substantial amounts of PGE2' when stimulated by a phagocytic stimulus such as zymosan particles coated with complement. Hydrocortisone, at a concentration of 10(-5) M, which proved to be effective in other biological systems, failed to inhibit phagocytosis and PG release.

MeSH Terms

Humans In Vitro Techniques Neutrophils/metabolism,physiology Phagocytosis Prostaglandins E/biosynthesis Zymosan

Chemicals

Prostaglandins E Zymosan

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Tolone G

Bonasera L

Brai M

Tolone C

References (16)

16 references, click to expand

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Nature. 1975 Dec 25;258(5537):739-41 PMID: 1207759
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Article Info

Journal

Experientia

Abbr.

Experientia

ISSN

0014-4754

DOI

10.1007/BF01951305

Published

1977-07-15

Pages

961-2

Language

English

Region

Switzerland

NLM ID

0376547

Subset

External Links

PubMed source DOI: 10.1007/BF01951305

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Prostaglandin production by human polymorphnuclear leucocytes during phagocytosis in vitro.

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