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PMID: 8195379 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Molecular epidemiology of nosocomial invasive aspergillosis.

Journal of clinical microbiology ·Vol. 32 ·No. 3 ·1994-03-00 ·Pages 684-90

Girardin H, Sarfati J, Traoré F, Dupouy Camet J, Derouin F, Latgé JP

Abstract

Moderately repeated DNA sequences were used to fingerprint strains of Aspergillus fumigatus isolated from patients with invasive aspergillosis and their hospital environment. Most strains sampled from the environment displayed different Southern blot hybridization patterns. A temporal survey of air contaminants showed that some strains can persist in the same environment for at least 6 months. Patients with invasive aspergillosis were infected by a single strain. In two patients, a nosocomial origin of infection was suggested.

MeSH Terms
Aspergillosis/epidemiology,genetics,microbiology Aspergillus fumigatus/genetics,isolation & purification Cross Infection/epidemiology,genetics,microbiology DNA Fingerprinting DNA, Fungal/genetics Environmental Microbiology Epidemiologic Methods Humans Repetitive Sequences, Nucleic Acid Species Specificity
Chemicals
DNA, Fungal
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Girardin H
Unité de Mycologie, Institut Pasteur, Paris, France.
Sarfati J
Traoré F
Dupouy Camet J
Derouin F
Latgé J P
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Article Info
Journal
Journal of clinical microbiology
Abbr.
J Clin Microbiol
ISSN
0095-1137
DOI
10.1128/jcm.32.3.684-690.1994
Published
1994-03-00
Pages
684-90
Language
English
Region
United States
NLM ID
7505564
PMCID
PMC263107
Subset
IM
External Links
PubMed source DOI: 10.1128/jcm.32.3.684-690.1994 PMC Full Text View journal details
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