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PMID: 775306 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Identification of a mutation within the structural gene for the a subunit of DNA-dependent RNA polymerase of E. coli.

Molecular & general genetics : MGG ·Vol. 145 ·No. 1 ·1976-04-23 ·Pages 19-22

Fujiki H, Palm P, Zillig W, Calendar R, Sunshine M

Abstract

An E. coli mutant rpoA109 unable to support the growth of phage P2 produces DNA-dependent RNA polymerase with an altered alpha subunit. Histidine is substituted for leucine in one tryptic peptide from the mutant alpha subunit. The existence of only one rpoA gene within the E. coli chromosome is indicated.

MeSH Terms
Amino Acid Sequence DNA-Directed RNA Polymerases Escherichia coli Genes Histidine Leucine Mutation
Chemicals
Histidine DNA-Directed RNA Polymerases Leucine
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Fujiki H
Palm P
Zillig W
Calendar R
Sunshine M
References (13)
13 references, click to expand
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Article Info
Journal
Molecular & general genetics : MGG
Abbr.
Mol Gen Genet
ISSN
0026-8925
DOI
10.1007/BF00331552
Published
1976-04-23
Pages
19-22
Language
English
Region
Germany
NLM ID
0125036
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00331552
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