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PMID: 7528804 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

Voltage-activated hydrogen ion currents.

The Journal of membrane biology ·Vol. 141 ·No. 3 ·1994-09-00 ·Pages 203-23

DeCoursey TE, Cherny VV

Abstract

暂无摘要

MeSH Terms
Amphibians Animals Carrier Proteins/metabolism Humans Hydrogen-Ion Concentration Ion Channels/physiology Kinetics Membrane Potentials Vertebrates
Chemicals
Carrier Proteins Ion Channels
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
DeCoursey T E
Department of Physiology, Rush Presbyterian St. Luke's Medical Center, Chicago, Illinois 60612.
Cherny V V
References (131)
131 references, click to expand
  1. Neutral phospholipids do not buffer at neutral pH.
    Biophys J. 1994 May;66(5):1733 PMID: 8061222
  2. Synthetic amphiphilic peptide models for protein ion channels.
    Science. 1988 May 27;240(4856):1177-81 PMID: 2453923
  3. Common channels for water and protons at apical and basolateral cell membranes of frog skin and urinary bladder epithelia. Effects of oxytocin, heavy metals, and inhibitors of H(+)-adenosine triphosphatase.
    J Gen Physiol. 1991 Apr;97(4):749-76 PMID: 1647438
  4. Hydrogen ion block of the sodium pore in squid giant axons.
    J Gen Physiol. 1983 Nov;82(5):599-618 PMID: 6315859
  5. The resting potential of moth muscle fibre.
    J Physiol. 1972 Sep;225(3):529-54 PMID: 5076386
  6. Rapidly activating hydrogen ion currents in perfused neurones of the snail, Lymnaea stagnalis.
    J Physiol. 1984 Jun;351:199-216 PMID: 6086903
  7. How do protons cross the membrane-solution interface? Kinetic studies on bilayer membranes exposed to the protonophore S-13 (5-chloro-3-tert-butyl-2'-chloro-4' nitrosalicylanilide).
    J Membr Biol. 1987;95(1):73-89 PMID: 3031309
  8. Intracellular pH regulation in epithelial cells.
    Annu Rev Physiol. 1986;48:377-88 PMID: 3010818
  9. The superoxide-generating NADPH oxidase of human neutrophils is electrogenic and associated with an H+ channel.
    Biochem J. 1987 Sep 1;246(2):325-9 PMID: 2825632
  10. Inward rectification in skeletal muscle: a blocking particle model.
    Pflugers Arch. 1978 Dec 28;378(2):173-6 PMID: 310542
  11. How pore mouth charge distributions alter the permeability of transmembrane ionic channels.
    Biophys J. 1987 Feb;51(2):297-311 PMID: 2435331
  12. Protons, the thylakoid membrane, and the chloroplast ATP synthase.
    Ann N Y Acad Sci. 1989;574:268-86 PMID: 2483874
  13. A voltage-dependent proton current in cultured human skeletal muscle myotubes.
    J Physiol. 1993 Oct;470:313-33 PMID: 7508503
  14. Thermogenic mechanisms in brown fat.
    Physiol Rev. 1984 Jan;64(1):1-64 PMID: 6320232
  15. Voltage-dependent block by amiloride and other monovalent cations of apical Na channels in the toad urinary bladder.
    J Membr Biol. 1984;80(2):153-65 PMID: 6090670
  16. Arachidonic acid stimulates the plasma membrane H+ conductance of macrophages.
    J Biol Chem. 1994 Feb 18;269(7):4736-45 PMID: 7508928
  17. Fluorescence studies of the secondary structure and orientation of a model ion channel peptide in phospholipid vesicles.
    Biochemistry. 1992 Jul 21;31(28):6608-16 PMID: 1378757
  18. Phorbol 12-myristate 13-acetate activates an electrogenic H(+)-conducting pathway in the membrane of neutrophils.
    Biochem J. 1992 Feb 1;281 ( Pt 3):697-701 PMID: 1371386
  19. Potassium channels as multi-ion single-file pores.
    J Gen Physiol. 1978 Oct;72(4):409-42 PMID: 722275
  20. Effects of growth factors on intracellular pH regulation.
    Annu Rev Physiol. 1986;48:363-76 PMID: 3010817
  21. Hydrogen bonded chain mechanisms for proton conduction and proton pumping.
    J Membr Biol. 1983;74(1):1-14 PMID: 6306243
  22. Abnormal activation of H+ conductance in NADPH oxidase-defective neutrophils.
    Proc Natl Acad Sci U S A. 1993 Jan 15;90(2):760-4 PMID: 8421713
  23. Potential, pH, and arachidonate gate hydrogen ion currents in human neutrophils.
    Biophys J. 1993 Oct;65(4):1590-8 PMID: 7506066
  24. Dynamics of ion transport systems in membranes.
    Physiol Rev. 1987 Oct;67(4):1296-331 PMID: 2446342
  25. A voltage-gated hydrogen ion current in the oocyte membrane of the axolotl, Ambystoma.
    J Physiol. 1984 Jul;352:243-63 PMID: 6086909
  26. Use of a fixed charge model to determine the pK of the negative sites on the external membrane surface.
    J Gen Physiol. 1970 Jun;55(6):822-5 PMID: 5424380
  27. Effect of changes in extracellular potassium on intracellular pH in principal cells of frog skin.
    Am J Physiol. 1992 Oct;263(4 Pt 2):F722-30 PMID: 1415743
  28. Slow changes in potassium permeability in skeletal muscle.
    J Physiol. 1970 Jul;208(3):645-68 PMID: 5499788
  29. Elevation in intracellular calcium activates both chloride and proton currents in human macrophages.
    J Membr Biol. 1994 May;140(1):13-30 PMID: 8051690
  30. Proton currents in human granulocytes: regulation by membrane potential and intracellular pH.
    J Physiol. 1993 Jul;466:329-44 PMID: 7692041
  31. Changes in the surface pH of voltage-clamped snail neurones apparently caused by H+ fluxes through a channel.
    J Physiol. 1988 Apr;398:313-27 PMID: 2455800
  32. Evidence for active H+ secretion by rat alveolar epithelial cells.
    Am J Physiol. 1989 Dec;257(6 Pt 1):L438-45 PMID: 2610271
  33. Effects of unstirred layers on membrane phenomena.
    Physiol Rev. 1984 Jul;64(3):763-872 PMID: 6377340
  34. The role of the electrochemical gradient in determining potassium fluxes in frog striated muscle.
    J Gen Physiol. 1968 May 1;51(5):193-203 PMID: 19873589
  35. Recovery of pHi in snail neurones exposed to high external potassium [proceedings].
    J Physiol. 1979 Nov;296:77P PMID: 43394
  36. A pH-sensitive and voltage-dependent proton conductance in the plasma membrane of macrophages.
    J Gen Physiol. 1993 Oct;102(4):729-60 PMID: 8270911
  37. Single channel H+ currents through reconstituted chloroplast ATP synthase CF0-CF1.
    EMBO J. 1989 Oct;8(10):2827-34 PMID: 2479536
  38. Extracellular access to the Na,K pump: pathway similar to ion channel.
    Science. 1993 Apr 2;260(5104):100-3 PMID: 7682009
  39. Transport of protons across membranes by weak acids.
    Physiol Rev. 1980 Jul;60(3):825-63 PMID: 6248908
  40. Quantitation of physical-chemical properties of the aqueous phase inside the phoE ionic channel.
    Biochim Biophys Acta. 1992 Aug 24;1109(2):141-8 PMID: 1381612
  41. Liquid junction potentials and small cell effects in patch-clamp analysis.
    J Membr Biol. 1991 Apr;121(2):101-17 PMID: 1715403
  42. Amiloride and its analogs as tools in the study of ion transport.
    J Membr Biol. 1988 Oct;105(1):1-21 PMID: 2852254
  43. Use of weak acids to determine the bulk diffusion limitation of H+ ion conductance through the gramicidin channel.
    Biophys J. 1988 Jan;53(1):25-32 PMID: 2449253
  44. The proton conducting F0-part of bacterial ATP synthases.
    Biochim Biophys Acta. 1984 Apr 9;768(1):1-27 PMID: 6231051
  45. Ionic selectivity, saturation, and block in gramicidin A channels. II. Saturation behavior of single channel conductances and evidence for the existence of multiple binding sites in the channel.
    J Membr Biol. 1978 Apr 26;40(2):97-116 PMID: 77904
  46. Structure and function of voltage-gated ion channels.
    Trends Neurosci. 1993 Dec;16(12):500-6 PMID: 7509519
  47. Effect of high pH on the plasma membrane potential and conductance in Elodea densa.
    J Membr Biol. 1992 May;128(1):63-9 PMID: 1501237
  48. Intracellular pH.
    Physiol Rev. 1981 Apr;61(2):296-434 PMID: 7012859
  49. Hydrogen ion currents and intracellular pH in depolarized voltage-clamped snail neurones.
    Nature. 1982 Oct 28;299(5886):826-8 PMID: 7133121
  50. Conformationally constrained alpha-helical peptide models for protein ion channels.
    Biopolymers. 1990 Jan;29(1):205-13 PMID: 1691664
  51. Na(+)-H+ antiport detected through hydrogen ion currents in rat alveolar epithelial cells and human neutrophils.
    J Gen Physiol. 1994 May;103(5):755-85 PMID: 8035162
  52. Vasopressin increases water permeability in inducing pores.
    Nature. 1980 Apr 17;284(5757):631-2 PMID: 6245372
  53. Superoxide generation by the electrogenic NADPH oxidase of human neutrophils is limited by the movement of a compensating charge.
    Biochem J. 1988 Oct 1;255(1):285-90 PMID: 2848506
  54. Development of a H(+)-selective conductance during granulocytic differentiation of HL-60 cells.
    Am J Physiol. 1994 May;266(5 Pt 1):C1263-70 PMID: 8203491
  55. The anomalous rectification and cation selectivity of the membrane of a starfish egg cell.
    J Membr Biol. 1974;18(1):61-80 PMID: 4854650
  56. Proteolipid of adenosinetriphosphatase from yeast mitochondria forms proton-selective channels in planar lipid bilayers.
    Biochemistry. 1982 Nov 9;21(23):5787-94 PMID: 6295439
  57. Regulation of the electrogenic H+ channel in the plasma membrane of neutrophils: possible role of phospholipase A2, internal and external protons.
    Biochem J. 1993 Jun 1;292 ( Pt 2):445-50 PMID: 7684901
  58. Intrinsic gating of inward rectifier in bovine pulmonary artery endothelial cells in the presence or absence of internal Mg2+.
    J Gen Physiol. 1990 Jul;96(1):109-33 PMID: 2212977
  59. Dependency of delta pH-relaxation across vesicular membranes on the buffering power of bulk solutions and lipids.
    Biophys J. 1986 Aug;50(2):265-76 PMID: 3017468
  60. Ion movement through gramicidin A channels. Studies on the diffusion-controlled association step.
    Biophys J. 1983 Feb;41(2):147-65 PMID: 6188502
  61. Proton conductance of the plasma membrane: properties, regulation, and functional role.
    Am J Physiol. 1993 Jul;265(1 Pt 1):C3-14 PMID: 8393283
  62. Regulation of lung surfactant secretion by intracellular pH.
    Am J Physiol. 1989 Dec;257(6 Pt 1):L354-60 PMID: 2514603
  63. Changes in membrane hydrogen and sodium conductances during progesterone-induced maturation of Ambystoma oocytes.
    Dev Biol. 1984 Oct;105(2):423-34 PMID: 6090243
  64. Transport of H+ and of ionic weak acids and bases.
    J Membr Biol. 1983;72(1-2):1-16 PMID: 6343604
  65. Na+/H+ exchange and growth factor-induced cytosolic pH changes. Role in cellular proliferation.
    Biochim Biophys Acta. 1989 Jan 18;988(1):73-97 PMID: 2535787
  66. Influenza virus M2 protein has ion channel activity.
    Cell. 1992 May 1;69(3):517-28 PMID: 1374685
  67. Regulation of intracellular pH in human neutrophils.
    J Gen Physiol. 1985 Mar;85(3):443-70 PMID: 2985737
  68. Mechanisms of potassium channel block in rat alveolar epithelial cells.
    J Pharmacol Exp Ther. 1990 Nov;255(2):459-72 PMID: 1700814
  69. Characterization of proton currents in neurones of the snail, Lymnaea stagnalis.
    J Physiol. 1989 Jun;413:75-89 PMID: 2557442
  70. Current understanding of the cellular biology and molecular structure of the antidiuretic hormone-stimulated water transport pathway.
    J Clin Invest. 1991 Jul;88(1):1-8 PMID: 2056113
  71. Proton flux mechanisms in model and biological membranes.
    J Membr Biol. 1989 Feb;107(2):91-103 PMID: 2469801
  72. The effect of zinc on calcium and hydrogen ion currents in intact snail neurones.
    J Exp Biol. 1989 Sep;145:455-64 PMID: 22912993
  73. Electrostatic radius of the gramicidin channel determined from voltage dependence of H+ ion conductance.
    Biophys J. 1988 Jan;53(1):33-8 PMID: 2449254
  74. Effects of intracellular H+ on the electrical properties of excitable cells.
    Annu Rev Neurosci. 1984;7:257-78 PMID: 6324645
  75. The after-effects of impulses in the giant nerve fibres of Loligo.
    J Physiol. 1956 Feb 28;131(2):341-76 PMID: 13320339
  76. Proton channels in snail neurones. Does calcium entry mimic the effects of proton influx?
    Ann N Y Acad Sci. 1989;574:287-93 PMID: 2483875
  77. A quantitative description of membrane current and its application to conduction and excitation in nerve.
    J Physiol. 1952 Aug;117(4):500-44 PMID: 12991237
  78. The MotA protein of E. coli is a proton-conducting component of the flagellar motor.
    Cell. 1990 Feb 9;60(3):439-49 PMID: 2154333
  79. Cytoplasmic hydrogen ion diffusion coefficient.
    Biophys J. 1992 Jun;61(6):1470-9 PMID: 1617134
  80. A model for anomalous rectification: electrochemical-potential-dependent gating of membrane channels.
    J Membr Biol. 1978 Dec 15;44(2):103-34 PMID: 731684
  81. Anionic lipid headgroups as a proton-conducting pathway along the surface of membranes: a hypothesis.
    Proc Natl Acad Sci U S A. 1983 Jan;80(1):160-4 PMID: 6296863
  82. Origin of the potassium and voltage dependence of the cardiac inwardly rectifying K-current (IK1).
    Biophys J. 1992 Feb;61(2):448-62 PMID: 1547332
  83. The NADPH-oxidase-associated H+ channel is opened by arachidonate.
    Biochem J. 1992 Apr 1;283 ( Pt 1):171-5 PMID: 1373602
  84. Ultrastructure, pharmacologic inhibition, and transport selectivity of aquaporin channel-forming integral protein in proteoliposomes.
    Biochemistry. 1994 Feb 15;33(6):1606-15 PMID: 8312280
  85. Na(+)-HCO3- symport modulates intracellular pH in alveolar epithelial cells.
    Am J Physiol. 1991 Jun;260(6 Pt 1):L555-61 PMID: 2058696
  86. Proton conductance by the gramicidin water wire. Model for proton conductance in the F1F0 ATPases?
    Biophys J. 1991 Jul;60(1):101-9 PMID: 1715764
  87. Membrane currents of internally perfused neurones of the snail, Lymnaea stagnalis, at low intracellular pH.
    J Physiol. 1986 Jul;376:477-91 PMID: 2432237
  88. pH recovery from intracellular alkalinization in Retzius neurones of the leech central nervous system.
    J Physiol. 1993 Mar;462:627-43 PMID: 8331595
  89. Cl-/HCO3- exchange modulates intracellular pH in rat type II alveolar epithelial cells.
    J Biol Chem. 1988 Apr 25;263(12):5599-606 PMID: 3356700
  90. The nature of the voltage-dependent conductance induced by alamethicin in black lipid membranes.
    J Membr Biol. 1973 Dec 31;14(2):143-76 PMID: 4774545
  91. ATP-sensitive Na(+)-H+ antiport in type II alveolar epithelial cells.
    Am J Physiol. 1991 Dec;261(6 Pt 1):C954-63 PMID: 1662908
  92. Water, proton, and urea transport in toad bladder endosomes that contain the vasopressin-sensitive water channel.
    J Gen Physiol. 1990 May;95(5):941-60 PMID: 2163434
  93. Proton conductance through phospholipid bilayers: water wires or weak acids?
    J Bioenerg Biomembr. 1987 Oct;19(5):427-42 PMID: 2826410
  94. The permeability of sodium channels to hydrogen ions in nerve fibres.
    Pflugers Arch. 1983 Feb;396(2):163-73 PMID: 6300755
  95. A scheme to account for the effects of Rb+ and K+ on inward rectifier K channels of bovine artery endothelial cells.
    J Gen Physiol. 1994 Apr;103(4):549-81 PMID: 8057078
  96. Ion transfer across lipid membranes in the presence of gramicidin A. II. The ion selectivity.
    Biochim Biophys Acta. 1972 Aug 9;274(2):313-22 PMID: 5049000
  97. Voltage-dependent intracellular pH in Helix aspersa neurones.
    J Physiol. 1987 Sep;390:433-52 PMID: 2450997
  98. Theory of passive proton conductance in lipid bilayers.
    J Bioenerg Biomembr. 1987 Oct;19(5):413-26 PMID: 2826409
  99. The action of calcium on the electrical properties of squid axons.
    J Physiol. 1957 Jul 11;137(2):218-44 PMID: 13449874
  100. Diffusion-limited ion flow through pores.
    Biochim Biophys Acta. 1976 Dec 2;455(2):493-509 PMID: 999924
  101. Proton channels, plasma membrane potential, and respiratory burst in human neutrophils.
    Eur J Haematol. 1993 Nov;51(5):309-12 PMID: 8282093
  102. Surface charges and ion channel function.
    Annu Rev Physiol. 1991;53:341-59 PMID: 1710438
  103. Calcium-hydrogen exchange by the plasma membrane Ca-ATPase of voltage-clamped snail neurons.
    Proc Biol Sci. 1993 Sep 22;253(1338):285-9 PMID: 19213150
  104. Number of water molecules coupled to the transport of sodium, potassium and hydrogen ions via gramicidin, nonactin or valinomycin.
    Biochim Biophys Acta. 1978 Sep 22;512(2):436-51 PMID: 81687
  105. Molecular mechanisms for proton transport in membranes.
    Proc Natl Acad Sci U S A. 1978 Jan;75(1):298-302 PMID: 272644
  106. Proton currents through amiloride-sensitive Na channels in hamster taste cells. Role in acid transduction.
    J Gen Physiol. 1992 Nov;100(5):803-24 PMID: 1335477
  107. Hydrogen ion currents in rat alveolar epithelial cells.
    Biophys J. 1991 Nov;60(5):1243-53 PMID: 1722118
  108. The transmembrane domain of influenza A M2 protein forms amantadine-sensitive proton channels in planar lipid bilayers.
    Virology. 1992 Sep;190(1):485-9 PMID: 1382343
  109. Inactivation of the potassium conductance and related phenomena caused by quaternary ammonium ion injection in squid axons.
    J Gen Physiol. 1969 Nov;54(5):553-75 PMID: 5346528
  110. The role of fixed and mobile buffers in the kinetics of proton movement.
    Biochim Biophys Acta. 1987 Jan 16;890(1):1-5 PMID: 3026469
  111. Bacterial adenosine 5'-triphosphate synthase (F1F0): purification and reconstitution of F0 complexes and biochemical and functional characterization of their subunits.
    Microbiol Rev. 1987 Dec;51(4):477-97 PMID: 2893973
  112. Channel-like function of the Na,K pump probed at microsecond resolution in giant membrane patches.
    Science. 1994 Mar 11;263(5152):1429-32 PMID: 8128223
  113. Inward rectification of a potassium channel in cardiac ventricular cells depends on internal magnesium ions.
    Proc Natl Acad Sci U S A. 1987 Apr;84(8):2560-4 PMID: 2436236
  114. Estimation of Na+ dwell time in the gramicidin A channel. Na+ ions as blockers of H+ currents.
    Biochim Biophys Acta. 1989 Dec 11;987(1):8-14 PMID: 2480817
  115. Mechanisms and consequences of pH-mediated cell regulation.
    Annu Rev Physiol. 1986;48:389-402 PMID: 3010819
  116. The use of quartz patch pipettes for low noise single channel recording.
    Biophys J. 1993 Oct;65(4):1666-77 PMID: 7506069
  117. Limitations of the whole cell patch clamp technique in the control of intracellular concentrations.
    Biophys J. 1990 Sep;58(3):759-70 PMID: 2169920
  118. Separation of hydrogen ion currents in intact molluscan neurones.
    J Exp Biol. 1989 Sep;145:439-54 PMID: 22912992
  119. Intracellular pH in the OK cell. I. Identification of H+ conductance and observations on buffering capacity.
    Am J Physiol. 1991 Dec;261(6 Pt 1):C1143-53 PMID: 1662906
  120. Protein kinase C activates an H+ (equivalent) conductance in the plasma membrane of human neutrophils.
    Proc Natl Acad Sci U S A. 1991 Dec 1;88(23):10816-20 PMID: 1720552
  121. Elements of proton pump models.
    Prog Clin Biol Res. 1984;164:103-11 PMID: 6097893
  122. Characterization of Na+-H+ antiport in type II alveolar epithelial cells.
    Am J Physiol. 1987 May;252(5 Pt 1):C490-8 PMID: 3034070
  123. Ion transfer across lipid membranes in the presence of gramicidin A. I. Studies of the unit conductance channel.
    Biochim Biophys Acta. 1972 Aug 9;274(2):294-312 PMID: 5048999
  124. Divalent cations and the activation kinetics of potassium channels in squid giant axons.
    J Gen Physiol. 1982 Jun;79(6):965-96 PMID: 6286846
  125. The electrogenic Na/HCO3 cotransporter.
    Kidney Int. 1989 Sep;36(3):392-402 PMID: 2687566
  126. Biochemical separation of delayed rectifier currents in frog short skeletal muscle fibres.
    J Physiol. 1985 Nov;368:379-92 PMID: 2416917
  127. Unpacking the incoming influenza virus.
    Cell. 1992 May 15;69(4):577-8 PMID: 1375129
  128. Internal pH changes associated with the activity of NADPH oxidase of human neutrophils. Further evidence for the presence of an H+ conducting channel.
    Biochem J. 1988 Apr 15;251(2):563-7 PMID: 2456757
  129. Modifier role of internal H+ in activating the Na+-H+ exchanger in renal microvillus membrane vesicles.
    Nature. 1982 Sep 9;299(5879):161-3 PMID: 7110335
  130. Diffusion of weak acids across lipid bilayer membranes: effects of chemical reactions in the unstirred layers.
    Science. 1973 Dec 21;182(4118):1258-61 PMID: 4752218
  131. Potassium ion current in the squid giant axon: dynamic characteristic.
    Biophys J. 1960 Sep;1:1-14 PMID: 13694549
Article Info
Journal
The Journal of membrane biology
Abbr.
J Membr Biol
ISSN
0022-2631
DOI
10.1007/BF00235130
Published
1994-09-00
Pages
203-23
Language
English
Region
United States
NLM ID
0211301
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00235130 View journal details
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