Mitogenic activity of staphylococcal exfoliative toxin.
Exfoliative toxin from Staphylococcus aureus was mitogenic for murine spleen cells. It was primarily active on T lymphocytes but also significantly stimulated B cells from the spleens of nude mice. The mitogenicity was not affected by simple sugar or alpha-methylpyranosides. N-acetylglucosamine and N-acetylgalactosamine inhibited its effect. Exfoliatin was as powerful a mitogen as the enterotoxins of S. aureus. Some significant differences between the mitogenic activity of the two toxins were demonstrated.
14 references, click to expand
-
The mitogenic effects of endotoxin and staphylococcal enterotoxin B on mouse spleen cells and human peripheral lymphocytes.J Immunol. 1970 Dec;105(6):1453-8 PMID: 4921787
-
Purification and some chemical and physical properties of staphylococcal enterotoxin A.Biochemistry. 1972 Feb 1;11(3):360-6 PMID: 4621755
-
Potentiation of the T-lymphocyte response to mitogens. I. The responding cell.J Exp Med. 1972 Jul 1;136(1):128-42 PMID: 5033417
-
A rapid method for the isolation of functional thymus-derived murine lymphocytes.Eur J Immunol. 1973 Oct;3(10):645-9 PMID: 4587740
-
Elicitation of selective T and B lymphocyte responses by cell surface binding ligands.Transplant Rev. 1972;11:87-130 PMID: 4588912
-
Combined effects of phytohemagglutinin and staphylococcal enterotoxin B on deoxyribonucleic acid synthesis during blast transformation in human lymphocytes.Infect Immun. 1974 Feb;9(2):384-90 PMID: 4361297
-
The biochemistry of plant lectins (phytohemagglutinins).Annu Rev Biochem. 1973;42(0):541-74 PMID: 4599386
-
Selective triggering of human T and B lymphocytes in vitro by polyclonal mitogens.J Exp Med. 1974 Jul 1;140(1):1-18 PMID: 4600344
-
Lymphocyte mitogens of staphylococcal origin.Ann N Y Acad Sci. 1974 Jul 31;236(0):362-75 PMID: 4547491
-
Evidence for cell-receptor activity in lymphocyte stimulation by staphylococcal enterotoxin.J Immunol. 1975 Jul;115(1):49-53 PMID: 1080166
-
The effect of staphylococcal enterotoxins on the primary in vitro immune response.J Immunol. 1975 Aug;115(2):575-8 PMID: 1097520
-
Purification and characterization of different types of exfoliative toxin from Staphylococcus aureus.Infect Immun. 1979 Jun;24(3):679-84 PMID: 468373
-
Nonspecific T-lymphocyte mitogenesis by pyrogenic exotoxins from group A streptococci and Staphylococcus aureus.Infect Immun. 1979 Sep;25(3):1075-7 PMID: 387590
-
THE ACTIVATION OF HUMAN PERIPHERAL LYMPHOCYTES BY PRODUCTS OF STAPHYLOCOCCI.Br J Haematol. 1965 Jul;11:421-31 PMID: 14317434
Contact
No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong
Qilu Normal University · Genelibs Bioinformatics Lab
750 Shunhua Rd, Jinan
2F, Bldg F, University Science Park
Tel: 0531-88819269
WeChat Official Account
Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.
Business Email
E-mail: product@genelibs.com
Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2
