Mosaicism in XX males.

Human genetics ·Vol. 45 ·No. 1 ·1978-11-24 ·Pages 103-6

Miró R, Caballín MR, Marina S, Egozcue J

Abstract

Three males with a 46,XX karyotype are described. In two of them, evidence of a Y-containing line was found. In the first case, 1 of 500 lymphocyte metaphases was 48,XXY. In the second, 1 of 400 oral mucosa cells contained a Y body. The proportion of low-grade XX/XXY mosaics found among XX males now stands at about 17%.

MeSH Terms

Humans Infertility, Male/genetics Karyotyping Male Mosaicism Sex Chromosome Aberrations/genetics

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Miró R

Caballín M R

Marina S

Egozcue J

References (18)

18 references, click to expand

Letter: Possible evidence for Xp plus in and XX Male.
Lancet. 1974 Jun 15;1(7868):1223 PMID: 4134689
Possible evidence of X-Y interchange in an XX male.
Lancet. 1977 Mar 5;1(8010):550 PMID: 65650
A clinical and cytogenetical study of three patients with male phenotype and apparent XX sex chromosome constitution.
Acta Endocrinol (Copenh). 1966 May;52(1):91-112 PMID: 4161439
Genetic intersexuality in goats.
J Reprod Fertil Suppl. 1969 May;7:Suppl 7:25-51 PMID: 5272213
Paternal transmission of maleness in XX human beings.
N Engl J Med. 1973 Mar 15;288(11):539-45 PMID: 4685451
X-Y chromosomal interchange in the aetiology of true hermaphroditism and of XX Klinefelter's syndrome.
Lancet. 1966 Aug 27;2(7461):475-6 PMID: 4161595
[Masculinization of XX males (author's transl)].
Humangenetik. 1974;21(3):245-53 PMID: 4847729
Analytic review: nature and origin of males with XX sex chromosomes.
Am J Hum Genet. 1972 Jan;24(1):71-105 PMID: 4622299
[Extended hypothesis of mosaicism as explanation for XX-men].
Humangenetik. 1974 Jul 15;23(2):161-2 PMID: 4848732
XXY cells in a predominantly XX human male: evidence for cell selection.
Pediatrics. 1966 Dec;38(6):982-5 PMID: 5928728
Chromosome measurements on an XXp+ male.
Hum Genet. 1976 May 19;32(2):141-2 PMID: 1270072
Sex-reversed mice: XX and XO males.
Cytogenetics. 1971;10(5):318-37 PMID: 5156366
Familial true hermaphrodism in three siblings: clinical, cytogenetic, histological and hormonal studies.
Humangenetik. 1975 Sep 10;29(2):99-109 PMID: 1236834
Two XX males in one family and additional observations bearing on the etiology of XX males.
Clin Genet. 1977 Feb;11(2):91-106 PMID: 837567
[Masculin phenotype in a child with a predominant 46, XX clone].
Pediatrie. 1975 Jan-Feb;30(1):73-6 PMID: 1129020
XX SEX CHROMOSOMES IN A HUMAN MALE. FIRST CASE.
Acta Med Scand. 1964;175:SUPPL 412:25-8 PMID: 14154995
A new case of XX-male (XX/XXY mosaic).
Hum Genet. 1977 Nov 2;39(1):131-7 PMID: 562834
Presence of brightly fluorescent material in testes of XX males.
J Med Genet. 1973 Jun;10(2):170-4 PMID: 4714585

Article Info

Journal

Human genetics

Abbr.

Hum Genet

ISSN

0340-6717

DOI

10.1007/BF00277581

Published

1978-11-24

Pages

103-6

Language

English

Region

Germany

NLM ID

7613873

Subset

External Links

PubMed source DOI: 10.1007/BF00277581 View journal details

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Mosaicism in XX males.

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